Environmental Toxicology and Ecotoxicology

Network toxicology focused investigation on the impacts of inorganic arsenic and cadmium on human and ecosystem health

This study uses network toxicology to analyze the toxic effects of inorganic arsenic and cadmium on human and ecosystem health, identifying 51 and 78 adverse outcome pathways respectively.

Copper-Induced Stress and Recovery Impacts on Organismal Phenotypes and the Underlying Proteomic Signatures in Botryllus schlosseri

This study identifies proteomic signatures and functional pathways in Botryllus schlosseri under copper stress and recovery, revealing molecular mechanisms of tolerance and adaptation.

Do pyrethroid insecticides influence sex ratios in agile frogs (Rana dalmatina)?

This study examines the effects of pyrethroid insecticides on sex ratios in agile frogs, finding male-biased phenotypic sex ratios due to female-biased mortality, not sex reversal.

Acclimation capacity of two-banded seabream juveniles (Diplodus vulgaris) to port conditions: implications for the role of ports as nursery habitats

This study examines how juvenile two-banded seabream exposed to port conditions show physiological and transcriptomic changes, suggesting potential acclimation strategies with long-term health implications.

Quantifying the effect of metal interactions on growth rate in Saccharomyces cerevisiae

The paper quantifies metal interaction effects on yeast growth using two metrics, finding nonadditive toxicity patterns linked to redox properties and gene overlap.

Adult killifish exposure to crude oil perturbs embryonic gene expression and larval morphology in first- and second-generation offspring

This study shows adult killifish exposure to crude oil causes developmental and gene expression changes in first- and second-generation offspring.

The molecular basis of the synergistic toxicity of Ni and Cu, common environmental co-contaminants

This study investigates the synergistic toxicity of Ni and Cu in E. coli, revealing disruptions in Fe-S cluster metabolism as a key mechanism.

On the Comparability between Studies in Predictive Ecotoxicology

This paper identifies criteria for reliable comparison between predictive ecotoxicology studies and highlights the lack of compliance with these criteria in existing research.

Intraspecific Variation in Gulf Killifish (Fundulus grandis) Avoidance of Contaminants

This study examines variation in Gulf killifish avoidance behavior toward petroleum-contaminated sediments across four estuaries, finding regional differences in response to fresh oil but not weathered oil.

Behavior and survival of earthworm (Eisenia andrei) to exposure to glyphosate-contaminated weed compost

This study evaluates the impact of glyphosate-contaminated weed compost on the behavior and survival of earthworms, finding reduced growth and mortality with higher herbicide doses.

Xenometabolome of Early-Life Stage Salmonids Exposed to 6PPD-Quinone

This study examines differences in 6PPD-Q biotransformation and metabolome responses among early-life stage salmonids, finding that brown trout detoxify it more effectively than sensitive species.

Brain-blood biomarkers take a walk on the wild side: glial responses to environmental conditions and individual traits in wild frogs

This study shows plasmatic GFAP levels in wild frogs correlate with environmental salinity, immune markers, and body condition, suggesting it as a biomarker of brain plasticity and stress responses.

Gene expression profile dynamics of earthworms exposed to ZnO and ZnO:Mn nanomaterials

This study examines the time-dependent gene expression changes in earthworms exposed to ZnO and ZnO:Mn nanomaterials, revealing transient effects on muscle biology and energy metabolism.

Exposure to epoxiconazole induces hyperlocomotion in adult zebrafish

This study investigates the behavioral effects of epoxiconazole exposure in zebrafish, finding increased locomotion but no significant effects on social preference or biochemistry.

Cytoprotective roles of "E3 ubiquitin ligases-NF-κB-autophagy" axis in Pacific oysters Crassostrea gigas exposed to phenanthrene

This study identifies a 'E3 ubiquitin ligases-NF-κB-autophagy' axis in Pacific oysters that is activated by phenanthrene and provides cytoprotection through autophagy.

A Cheminformatics Workflow for Higher-throughput Modeling of Chemical Exposures from Biosolids

The paper presents an R workflow that automates data preparation for the Biosolids Screening Tool, enabling faster and more transparent chemical exposure modeling from biosolids.

Amazon biodiversity is at risk from metal contamination due to mining activity

The paper quantifies metal contamination exposure across Amazon biodiversity, finding 66% of species are exposed to mining-associated metals.

Analysis of spectral and photosynthetic response variations of Cystoseira spp. exposed to Chromium

This study examines how different Cystoseira species respond to chromium exposure by analyzing spectral and photosynthetic changes, identifying key wavelengths for remote sensing applications.

Hierarchical Approaches for Integrating Sparse, Multivariate Toxicological Effect Data in Whole Organism Molecular Dynamics Models

The paper uses Bayesian hierarchical ODE models to integrate sparse, multivariate toxicity data from zebrafish embryos, improving parameter estimation despite experimental variability and model inadequacy.

Multiple stressors in the Anthropocene: Urban evolutionary history modifies sensitivity to the toxic effects of crude oil exposure in killifish

The paper shows that urban killifish populations resistant to PCBs are also resilient to crude oil toxicity due to shared molecular mechanisms.

Exposure to neodymium blunts the hypoxic ventilatory response in fathead minnows (Pimephales promelas)

This study examines if neodymium exposure reduces the hypoxic ventilatory response in fathead minnows, finding a 31% decrease in the response with no detectable gill accumulation.

Ecological Toxicity Effects of Marine Pollutants Based on Microalgal Locomotory Behavior

This study uses microalgal motility to assess marine pollutant toxicity, finding significant inhibition of locomotory behavior by copper and phenol with dose-response relationships and strong correlation with traditional toxicity tests.

Cadmium tolerance is associated with tissue-specific plasticity of metallothionein gene expression in Gammarus fossarum field populations

This study links Cd tolerance in Gammarus fossarum to mt1 gene expression plasticity in gills and caeca, showing transgenerational effects and inducibility under Cd exposure.

The multi-level effect of chlorpyrifos during clownfish metamorphosis

This paper investigates how chlorpyrifos exposure disrupts thyroid hormone signaling and metamorphosis in clownfish larvae, showing impaired white band formation and body shape changes, with TH treatment reversing some effects.

Sub-chronic and acute toxicity of 6PPD-quinone to early-life stage rainbow trout (Oncorhynchus mykiss)

This study assesses the acute and sub-chronic toxicity of 6PPD-quinone to early-life stage rainbow trout, finding higher sensitivity compared to sub-adults and developmental abnormalities.

AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers

The paper uses AI to assess chronic chemical risks in river water, identifying pharmaceuticals as key risk drivers and fish as the most vulnerable group.

Discoloration of the Cephalothorax in Pandalus borealis and its Correlation with Internal Cadmium Concentration

This study examines the link between cephalothorax discoloration in Pandalus borealis shrimp and cadmium concentration, finding no significant correlation.

Trace Elements in Fish: Assessment of bioaccumulation and associated health risks.

Across five fish species at Pakistan's Punjnad headworks, Wallago attu accumulated most Cd, Cu, Pb and Ni, and modelled total hazard quotients exceeded 1 for every species.

Daphnids Can Safeguard the Use of Alternative Bioassays to the Acute Fish Toxicity Test: A Focus on Neurotoxicity

This study evaluates the sensitivity of daphnids compared to fish for neurotoxic chemicals, finding daphnids often more sensitive and suggesting their use as an alternative to fish toxicity tests.

Gene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish (Fundulus heteroclitus)

This study compares gene expression and DNA methylation responses to hypoxia in toxicant-resistant and reference killifish populations, finding altered transcriptional and epigenetic responses in the resistant group.