Topic · Pulmonary and Respiratory Medicine · Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Alveolar epithelial cell plasticity and injury memory in human pulmonary fibrosis

Taylor Sterling Adams, Jonas C. Schupp, Agshin Balayev, Johad Khoury, A. Justet, Fadi Nikola, Laurens De Sadeleer, Juan Cala-García, Marta Zapata‐Ortega, Panayiotis V. Benos, John E. McDonough, Farida Ahangari, Mélanie Königshoff, Jun Ding, Robert Homer, , Naftali Kaminski

Single-nucleus multiomic and ex vivo lung slice profiling of human idiopathic pulmonary fibrosis identifies Alveolar Intermediate cells bridging alveolar and Aberrant Basaloid states and reveals AP-1 chromatin injury memory.

bioRxiv · Jun 10, 2025 · PreprintCell Biology✦ In-depth digest

Image-based spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis

Annika Vannan, Ruqian Lyu, Arianna L. Williams-Katek, Nicholas M. Negretti, Evan D. Mee, Joseph Hirsh, Samuel Hirsh, Niran Hadad, David S. Nichols, Carla L. Calvi, Chase J. Taylor, VV Polosukhin, Ana Paula Moreira Serezani, A. Scott McCall, Jason J. Gokey, , Nicholas E. Banovich

Xenium profiling of 343 genes in 1,126,820 nuclei from 19 human lungs maps fibrosis niches and orders alveolar remodeling from alveolar-capillary disruption to SPP1+ macrophage accumulation.

Nature Genetics · Feb 3, 2025Peer-reviewedGenomics✦ In-depth digest