Nanocluster Synthesis and Applications

Programmable Assembly of DNA Tetrahedra Bearing Atomically Precise Gold Nanoclusters: Stoichiometric Control and Molecular-Level Characterization

This study develops a method to synthesize programmable DNA tetrahedra with controlled numbers of AuNCs and characterizes their composition using mass spectrometry.

One-Pot NADH-Mediated Physiological Redox-Controlled Synthesis of Papain-Stabilized Copper Nanoclusters with Preserved Bioactivity for Efficient Drug Delivery

This paper develops a one-pot, physiologically compatible synthesis of papain-stabilized copper nanoclusters using NADH as a reducing agent, showing enhanced helical stability and effective drug delivery with reduced IC50 in cancer cells.

Spatially Organized DNA-templated Silver Nanoclusters as Potent Antimicrobial Agents for ESKAPE Infections

This study develops DNA-templated silver nanoclusters as antimicrobial agents effective against antibiotic-resistant pathogens and demonstrates their dual therapeutic and imaging capabilities.

Self-Assembled siRNA-Gold Supraclusters Detected at the Single-Molecule Level in the NIR-II Window

This study reports the self-assembly of NIR-II emitting AuNCs guided by siRNA, demonstrating their stability, photoluminescence, and potential for imaging and gene therapy.

Interplay Between Intrinsically Disordered Proteins and Atomically Precise Gold Nanoclusters Modulates their Optical Properties

This study investigates how intrinsically disordered proteins modulate the optical properties of gold nanoclusters through position-specific anchoring, leading to enhanced photoluminescence.

Au18(L-NIBC)14 targets ASC oligomerization for autoimmune disease treatment

This study identifies Au18(L-NIBC)14 as a gold nanocluster that targets ASC oligomerization, reducing inflammasome activation and improving symptoms in autoimmune disease models.