Saffron Plant Research Studies

Chromosomal variability in a clonal crop: Somaclonal change follows the emergence of triploid saffron crocus

The paper identifies chromosomal and genetic variability in saffron crocus cultivars, revealing regional somaclonal lineages despite clonal origin.

Exploring the Antidepressant Effects of Saffron Constituents: Targeting Dopamine and Serotonin Transport Proteins, and Monoamine Oxidase-B: An in Silico Evidence-Based Study

This study investigates the antidepressant potential of saffron compounds through molecular docking and pharmacokinetic analysis, finding safranal as a promising natural inhibitor of dopamine transporter with favorable BBB permeability and binding affinity.

Time-Resolved Transcriptomics Reveal Spliceosomal Disruption and Senescence Pathways in Crocin-Treated Hepatocellular Carcinoma Cells

This study uses time-resolved transcriptomics to show crocin disrupts the spliceosome and activates senescence pathways in hepatocellular carcinoma cells, with dose-dependent effects on gene expression and splicing.

Crocin inhibited amyloid-beta (Aβ) generation via promoting non-amyloidogenic APP processing and suppressed ER stress UPR signaling in N2a/APP cells

Neuroprotective effects of crocin I and II in an ischemia-reperfusion injury model

This study investigates the neuroprotective effects of crocin I and II in a rat ischemia-reperfusion injury model, finding they reduce Casp3 and Nfkb1 mRNA expression and improve antioxidant capacity.

Transcriptome from saffron (Crocus sativus) plants in Jammu and Kashmir reveals abundant soybean mosaic virus transcripts and several putative pathogen bacterial and fungal genera