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This study investigates how aging affects aortic MMP activity and aneurysm development using MMP-targeted imaging, finding increased MMP activity and worse survival in older mice.

The paper introduces Lo3DP, a low-cost 3D-printer-based microfluidic platform for lab automation, achieving high accuracy and programmability in droplet manipulation and assays.

This paper designs orthogonal TCR β interfaces to prevent mispairing in dual-TCR therapeutics, achieving high pairing fidelity and demonstrating enhanced potency in targeting cancer antigens.

This paper develops tunable citrate-based polymer scaffolds for regenerative engineering by modulating crosslinking density and network topology to achieve broad mechanical performance.

This paper develops a noncovalent method to functionalize piezoelectric scaffolds with bioactive nanocarriers, enabling sustained cytokine signaling for tissue and immune engineering.

This paper evaluates a FRET-based biosensor for real-time pH monitoring as an indicator of food spoilage, showing pH-responsive signals in both buffer solutions and chickpea paste.

This paper introduces a passive-oxygenation silicone bioreactor for cellular agriculture, demonstrating improved labor productivity and cost efficiency in biomass production.

This study examines how postmortem intervals affect quantitative MRI signals in unfixed and fixed pig brains, finding that PMI significantly impacts T1 relaxation times but not T2 or T2*.

This paper demonstrates scalable hydrogen production using microalgae and provides techno-economic analysis showing potential cost reductions for industrial applications.

This study uses sulfated hydrogels to show that ECM sulfation enhances tumor cell survival and reduces chemotherapeutic efficacy by modulating stress responses and drug efflux.

The paper identifies optimal geometric characteristics for cubically symmetric and triply periodic scaffolds to enhance cell migration by avoiding nucleus deformation and ensuring pore accessibility.

This study introduces an immune-competent colon assembloid model to investigate how neuroinflammation affects colonic motility, finding impaired neuronal regeneration and smooth muscle remodeling as key mechanisms.

The paper develops aptamer-based DNA nanoswitches for detecting proteins, demonstrating dual detection of thrombin and VEGF.

This paper develops a bacteria-mimetic bioadhesive using a Vibrio cholerae-derived peptide to achieve strong, non-covalent mucus adhesion and drug delivery.

This paper shows that engineered Vibrio natriegens lysate can replace fetal bovine serum and fibroblast-like growth factor 2 in cell culture media for cultivated meat, supporting cell proliferation and differentiation.

The paper introduces ME-SPICy, a microfluidic platform for targeted electroporation of selected cell subpopulations using antibody-conjugated microparticles and impedance detection, achieving 5-fold enrichment of lymphocytes.

This paper uses a digital twin of essential tremor to train deep neural networks for predicting muscle activation, achieving 81-83% accuracy in synthetic data.

This paper uses wide-field iSCAT microscopy and spectral exponent analysis to label-free map subcellular dynamics, distinguishing between different cellular states and cancer subtypes.

This paper designs novel acyl carrier protein variants using a computational method, showing they can undergo post-translational modification despite lacking the canonical helical structure.

This study examines agarose hydrogels' dynamic mechanical properties under varying humidity and polymer concentration, finding optimal energy dissipation at intermediate network densities.