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363,000+ bioRxiv and medRxiv preprints, including those later published in peer-reviewed journals, across 26 biological disciplines.
Recent preprints
- NeurosciencebioRxivPreprint
Heterogeneous Instructive Signals Enable Ensemble Learning in Cerebellar Cortex
Benjamin S. Ruben, Cengiz Pehlevan
This paper proposes a model of associative learning in cerebellar cortex ensembles using heterogeneous plasticity, showing improved pattern recognition performance with ensemble size.
1 citation - NeuroscienceNeuropsychologiaPeer-reviewed
Distinct and shared neural resources between processing of dynamic physical objects and spatial working memory
The paper investigates whether neural resources for processing dynamic physical objects overlap with those for spatial working memory, finding shared engagement in frontoparietal cortex.
- NeurosciencebioRxivPreprint
Spatial attention and lateralized pre-stimulus alpha shape iconic memory via inhibition
The paper investigates how spatial attention and pre-stimulus alpha oscillations influence iconic memory, finding that both contribute to suppression of irrelevant visual input through separate mechanisms.
DOI 10.64898/2026.07.31.742006 - NeurosciencebioRxivPreprint
Sources of Variability in Normative Cerebral FDG-PET imaging
Giordana Salvi de Souza, Guilherme Povala, Guilherme G. Schu Peixoto…·Laura Willers Souza
The paper investigates variability in FDG-PET imaging due to scanner manufacturer, reference region, age, and sex, and generates covariate-adjusted normative data.
- NeurosciencebioRxivPreprint
HippoGenes: A robust workflow for subregional transcriptomic profiling of the human hippocampus
Alexander Ngo, Sara Larivière, Jessica Royer…·Boris C. Bernhardt
HippoGenes creates transcriptomic maps of the human hippocampus using spatial statistical models and the Allen Human Brain Atlas, enabling subregional gene expression analysis and disease-related molecular decoding.
DOI 10.64898/2026.08.04.742581 - NeurosciencebioRxivPreprint
Longitudinal Characterization of a Novel Class of Recurrent, Stereotyped Neurophysiological Events in an Advanced Meditator
Alejandro Luis Callara, Francesco Bossi, Jampa Soepa…·Bruno Neri
The paper reports recurrent, stereotyped EEG patterns in an advanced meditator over 13 months, showing consistent neurophysiological dynamics across sessions.
DOI 10.64898/2026.07.31.741981 - NeurosciencebioRxivPreprint
Seasonal photoperiod cycling reduces inter-individual variability in mu-opioid receptor density in rats
Lihua Sun, Heidi Liljenbäck, Jenni Virta…·Anne Roivainen
This study shows that seasonal photoperiod cycling reduces inter-individual variability in mu-opioid receptor density in rats compared to constant photoperiod conditions.
DOI 10.64898/2026.08.03.742441 - NeurosciencebioRxivPreprint
Kappa Opioid-Oxytocin Interactions During Long-Term Partner Separation: Insights from PET Imaging in Titi Monkeys (Plecturocebus cupreus)
John P. Paulus, Claudia Manca, Alita Jesal D Almeida…·Karen Lisa Bales
This study uses PET imaging in titi monkeys to examine KOR availability and plasma OT changes during partner separation, finding reduced KOR in nucleus accumbens and sex-dependent OT responses.
DOI 10.64898/2026.07.30.739928 - NeurosciencebioRxivPreprint
Pupil Dynamics reflect Compensatory Control during Continuous Motor-Control following Cognitive Demand
Esther A. Semmelhack, Annekathrin Schacht
This study examines how pupil dynamics reflect compensatory control after cognitive demand and their relation to motor performance.
- NeurosciencebioRxivPreprint
Global Structural Brain-Age in Adolescence: Application of an Established Method to Short-Interval, Longitudinal Data
Amanda Boyes, Laura K. M. Han, Maddison Crethar…·Daniel Francis Hermens
The paper applies an existing brain-age model to longitudinal adolescent MRI data, finding moderate consistency but issues with accuracy and age-related bias.
- NeurosciencebioRxivPreprint
Denoising the central autonomic network: characterizing processes jointly associated with arousal and non-neuronal physiological artefacts in dynamic fMRI analyses
Mary Miedema, Rémi Dagenais, Mohammad Torabi…·Georgios D. Mitsis
This study investigates how denoising systemic low frequency oscillations affects dynamic signatures of central autonomic regulation and their relation to physiological states using multimodal data.
DOI 10.64898/2026.07.30.741873 - NeurosciencebioRxivPreprint
Hv1 proton channel is essential for splenic antibacterial defense and immune homeostasis during the chronic phase of traumatic brain injury in male mice
Zhuofan Lei, Romeesa Khan, Yun Li…·Junfang Wu
This study shows that Hv1 deficiency in mice leads to increased mortality and immune dysfunction after TBI, with significant effects on splenic antibacterial defense and immune homeostasis.
DOI 10.64898/2026.07.31.742029 - NeurosciencebioRxivPreprint
Isoflurane and surgery aggravate APOE4-dependent lipid dysregulation and neural dysfunction, leading to neurological impairment in male mice
Yun Li, Yuanyuan Ji, Çoşar Uzun…·Junfang Wu
This study shows that isoflurane anesthesia and surgery worsen lipid dysregulation and neural dysfunction in APOE4 mice, leading to neurological impairments.
DOI 10.64898/2026.07.31.742028 - NeurosciencebioRxivPreprint
Model based analysis of the orderly size-wise activation observed with sinusoidal low frequency alternating current stimulation of peripheral nerves
This paper uses computational modeling to show that sinusoidal low frequency alternating current (LFAC) stimulation of peripheral nerves produces orderly fiber recruitment based on size, unlike conventional pulse stimulation, by leveraging membrane accommodation properties.
DOI 10.64898/2026.08.03.742412 - NeuroscienceeLifePeer-reviewed
Human Brain-Wide Activation of Sleep Rhythms
Haiteng Wang, Qihong Zou, Jinbo Zhang…·Yunzhe Liu
This study identifies brain-wide activation patterns during sleep rhythms using EEG and fMRI, showing thalamus and hippocampus involvement in memory processes.
DOI 10.7554/elife.103956.4 - NeurosciencebioRxivPreprint
Behavioural and neural mechanisms for stochastic choices in mixed-strategy games
Joanna Aloor, Timothy P.H. Sit, Oliver M. Gauld…·Chunyu A. Duan
This study investigates how mice and monkeys generate stochastic choices in competitive games, finding that neural circuits decouple reward signals from future choices to achieve unpredictability.
DOI 10.64898/2026.07.29.741515 - NeuroscienceScientific DataPeer-reviewed
A standardized naturalistic audio stimuli database with unsupervised labeling
Anas Al-Naji, Ricarda I Schubotz, Anoushiravan Zahedi
The paper introduces a naturalistic audio stimuli database with unsupervised labeling, resulting in 10 semantic categories for diverse experimental use.
DOI 10.1038/s41597-026-08034-0 - NeurosciencebioRxivPreprint
Regional cerebral arterial elasticity is associated with cardiovascular health in cognitively healthy older adults
J. D. Johnson, Nicholas Ware, Sarah J. Johnson…·Frini Karayanidis
This study examines the relationship between cerebral arterial elasticity and cardiovascular health in older adults, finding that higher cardiovascular risk burden is associated with lower cerebral arterial elasticity.
- NeurosciencebioRxivPreprint
Is that clear? Robust electrophysiological measures of the effects of prior knowledge on degraded speech perception.
Shyanthony R. Synigal, Wen Li, Megan Rose Serody…·Edmund C. Lalor
The paper investigates how prior knowledge affects degraded speech perception using EEG, finding strong neural correlates of perceptual evidence accumulation influenced by prior information.
DOI 10.64898/2026.07.31.742060