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This study shows fibronectin in the hair follicle stem cell niche regulates regeneration by integrating signals through integrin and SLC3A2.

The paper examines sex-specific metabolic differences in offspring of obese mothers, showing females have better metabolic outcomes due to more efficient transcriptional and posttranscriptional reprogramming.

This study shows that STIM1 maintains peripheral coupling in vascular smooth muscle cells, essential for contractility, independent of ER Ca2+ store depletion.

This study shows that systemic TB4 gene therapy prevents podocyte injury and albuminuria in mice with Adriamycin-induced glomerular disease.

This study examines how deviations of the endogenous circadian period from 24h correlate with aging biomarkers and cognitive decline in aged non-human primates.

This study examines how temperature affects the behavior and molecular responses of Neptunea cumingii, showing significant physiological and transcriptomic changes outside the optimal temperature range of 8–16°C.

This paper introduces an integral equation to model homeostasis in living organisms and demonstrates its ability to quantitatively represent various biological situations.

This study shows that rapamycin increases plasma glucose and worsens age-related osteoarthritis in guinea pigs, despite inhibiting mTORC1 signaling.

This study deletes SOD2 in skeletal muscle of adult mice and finds no major metabolic impairment but altered lipid metabolism and mitochondrial abundance.

This study shows that genetic inhibition of SGK1 reduces obesity-related atrial fibrillation in mice by decreasing fibrosis, inflammation, and altering electrophysiology.

This study compares the effects of high intensity interval training (HIIT) and voluntary wheel running (VWR) on physical function in adult and older mice, finding that both improve function but older mice benefit less.

This paper reviews and analyzes studies on the relationship between glucocorticoids and telomere length in non-primate vertebrates, finding no significant effect of short-term glucocorticoid elevations on telomere length.

The paper develops an algorithm to visualize snoring duration through acoustic analysis, showing higher reproducibility with digital recordings than a smartphone app.

This study shows that loss of intestinal ChREBP reduces glucose absorption and delays glycemic responses by impairing sugar transporters and enzymes.

This study shows that senescent cells temporarily accumulate during murine fracture healing, and their removal with senolytics accelerates healing, unlike in skin wounds.

This study identifies Neuropeptide F (NPF) in Drosophila as a sugar-responsive incretin-like hormone that regulates lipid metabolism via glucagon-like and insulin-like hormones.

This study identifies age-related transcriptomic changes in skeletal muscle of older mice that correlate with declines in physical function.

This study compares the force profile of kettlebell swings and deadlifts in older adults, finding higher peak force in swings than deadlifts, with similar effects using lighter kettlebells.