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This study shows that transvalvular unloading reduces arrhythmias after myocardial ischemia/reperfusion by preserving coronary microcirculation and cardiomyocyte nanostructure in a porcine model.

This study shows that sexually selected infanticide can promote species coexistence by generating density-dependent demographic costs that enhance self-limitation and reduce competitive exclusion.

mito-overview integrates mitochondrial coverage, allele fractions, annotations, and read co-occurrence to identify and analyze candidate variants in mitochondrial genomic reports.

This study tests 50-Hz and theta-burst stimulation of the hippocampus and entorhinal area in monkeys and finds no memory enhancement, but significant transient memory disruption across multiple conditions.

This study identifies POSH as a genetic modifier of Myc function in Drosophila through a genetic screen and functional analysis.

SMART, a multi-agent framework, transfers findings from single-cell RNA-sequencing cancer studies to other cancer types, identifying cross-cancer prognostic signatures and generating new hypotheses.

This study uses drift-diffusion modeling on larval zebrafish to show that evidence integration dynamics develop during early stages and are altered by disease-linked mutations.

This study identifies CENPB and LIC2 as critical kinetochore proteins required for KSHV episome persistence and replication through a shRNA-based screen of kinetochore-associated genes.

This study investigates how reward influences hippocampal spatial maps by separating its effects on map usage and structure through a two-pathway model.

The paper introduces GTPase biosensors that report activity without blocking ligand interactions, revealing feedback mechanisms in Rac1 regulation.

The paper develops a framework to understand how biotic interactions modulate global change effects on plant communities and finds herbivores mitigate negative impacts while plant competition has mixed effects.

This study shows that L-DOPA improves certain motor features but not others in a bimanual string-pulling task in Parkinsonian rats.

This study links genomic diversity to phenotypic virulence in Pseudomonas aeruginosa by analyzing multiple strains and their functional behaviors.

This study shows glioblastoma hijacks astrocyte ribosomes via tunneling nanotubes, reprograms the tumor translatome to promote malignancy, and identifies INTS12 as a therapeutic target.

This study evaluates the performance of three large language models on basic bioinformatics tasks compared to human performance, finding LLMs match human accuracy in some areas but struggle with complex tasks like sequence alignment.

The paper investigates the genomic basis of hypoxia tolerance divergence between two eastern oyster populations, finding that gene regulation, not protein-coding evolution, drives population-specific differences.

This paper introduces NanoBlocks, a method to convert affinity binders into fluorescent biosensors by adding competitive peptides, demonstrating their use in detecting targets in vitro and in cells.

PhageFlare predicts functions for phage proteins with no structural matches, outperforming baselines and annotating many previously unresolved proteins.

The paper shows that prematurity disrupts cerebellar development by altering developmental trajectories and causing lineage-specific asynchrony in cell maturation.

Rugnux processes diffraction images from synchrotrons and XFELs into merged data and initial structures quickly and efficiently on a single GPU.