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This study shows macaques monitor their partner during cooperative tasks, with increased head turns when the partner makes errors.

corrdeconv corrects deconvolution errors by addressing misread disease cell states as abundance, outperforming existing methods and reducing refuted effects.

The paper evaluates how well population-level connectome harmonics represent individual brains across different dimensions and finds they can be useful despite not perfectly matching individual data.

This study investigates the effects of intranasal opioid administration in mice, revealing changes in dopamine and opioid dynamics and associated behaviors.

This paper engineers proteins to restore and enhance neurotransmitter release by reconstituting active zone functions in neurons.

This paper introduces RLMHelix, an alignment-free method to discover conserved RNA structures in the human genome, identifying new candidates that correlate with RNA-binding protein interactions.

This study shows that memories of complex narrative events are spontaneously reactivated during rest, but reactivation is linked to gist-like recall rather than strengthening episodic memory details.

This study shows mucosal cytokines drive Gd-IgA1 production in IgAN by expanding specific B cell populations, supporting therapies targeting mucosal immunity.

Deep proteomics of 997 treatment-naïve colorectal cancers defines six subgroups, splitting chromosomally unstable tumors into three and revealing a rare adverse subgroup, with H&E slide benchmarks.

This study uses RNA-seq to analyze the transcriptomic effects of butyrate on human lymphoblastoid cell lines, identifying dysregulated genes in multiple disease-related pathways.

The paper shows that HIV-1 integrase C-terminal domain mutations affect sensitivity to ALLINIs by altering gRNA binding, despite being distant from the drug binding site.

The paper identifies brain-peripheral DNA methylation sites (BrESS) that consistently predict brain methylation across tissues, showing they are not linked to disease heritability.

This study identifies Leptospira species in dogs and rodents in Thailand, revealing new pathogen diversity and environmental associations.

The paper calibrates AlphaGenome Variant Impact (AVI) and SpliceAI2 scores for variant classification, showing their performance across different variant classes and comparison methods.

The paper investigates sex-specific regulation of CaMKII in Drosophila, showing differences in steady-state and activity-dependent levels between males and females without affecting plasticity.

This paper introduces a reduced-observable dynamic mode decomposition method for analyzing theta and beta EEG activity in working memory tasks, finding correlations between oscillatory power and memory encoding events.

This study identifies METTL3-mediated m6A modification as a regulator of triglyceride metabolism in ALS skeletal muscle, alleviating atrophy through ACSL1 expression.

The paper shows inherited protein-truncating variants contribute to developmental disorders through partial gene expression loss, affecting ~20% of children with such variants.

A length- and mutation-load-corrected homoplasy screen of 1,813 MDR-TB genomes flags idsA2; its loss raises pretomanid MIC fourfold, delamanid and ethambutol twofold, via isoprenoid flux redirection.

This study uses HS-AFM to show yeast TOM complexes predominantly form trimers that dynamically dissociate into dimers and monomers, revealing structural and dynamic features of the TOM complex.