Daniel W. Wesson

Neuroinflammation is an early pathological process in a mouse model of prodromal Parkinsons disease

This study shows that neuroinflammation occurs early in a mouse model of prodromal Parkinson's disease before neuronal loss, linking Syn pathology to olfactory dysfunction.

Disruption of opioid and mesolimbic dopamine dynamics and behavior upon intranasal delivery of opioids in mice

This study investigates the effects of intranasal opioid administration in mice, revealing changes in dopamine and opioid dynamics and associated behaviors.

In-dwelling microfluidic device for precise and reliable intranasal drug delivery during freely-moving behavior

The paper develops a microfluidic device for precise intranasal drug delivery in freely-moving mice and validates its use for studying cocaine's effects.

Midbrain dopamine neuronal activity modulates splenic immunity through a brain-to-body circuit

This study shows midbrain dopamine neurons modulate splenic immunity via a brain-to-body circuit involving the DVC and celiac ganglion, reducing spleen weight and naive CD4+ T-cell populations.

Bidirectional modulation of negative emotional states by parallel genetically-distinct basolateral amygdala pathways to ventral striatum subregions

The paper identifies two genetically distinct BLA pathways to the ventral striatum that bidirectionally modulate negative emotional states through projection-specific mechanisms.

Sniffing can be initiated by the actions of dopamine on ventral striatum neurons

This study shows dopamine in the ventral striatum initiates sniffing by modulating respiratory rate and neuronal activity.

Strawberry additive increases nicotine vapor sampling and systemic exposure but does not enhance Pavlovian-based nicotine reward in mice

This study investigates how a strawberry additive affects nicotine reward and exposure in mice, finding increased vapor sampling but no enhancement of reward.

Glucagon-like peptide-1 receptors in the gustatory cortex influence food intake

This study shows that GLP-1R+ neurons in the gustatory cortex regulate food intake in mice, with effects dependent on diet type.

Organization and engagement of a prefrontal-olfactory network during olfactory selective attention

This study identifies a prefrontal-olfactory network involved in olfactory selective attention, showing coordinated activity in mPFC and olfactory regions during attention shifts.

Self-grooming promotes social attraction in mice via chemosensory communication

The paper shows that self-grooming in mice increases social attraction through chemosensory cues, using optogenetic induction of grooming behavior.

Perturbation of in vivo neural activity following α-Synuclein seeding in the olfactory bulb

This study shows that α-Synuclein seeding in the olfactory bulb leads to altered odor-evoked neural activity in the olfactory system.

Alterations in odor hedonics in the 5XFAD Alzheimer's disease mouse model and the influence of sex

The paper investigates odor hedonics in 5XFAD Alzheimer's disease mice, finding prolonged odor investigation and altered preferences in females.

A neural system that represents the association of odors with rewarded outcomes and promotes behavioral engagement

The paper investigates how odor-reward associations are represented in brain regions and how these representations influence behavior during learning.

Deficits in olfactory sensitivity in a mouse model of Parkinson's disease revealed by plethysmography of odor-evoked sniffing

This study shows that injecting α-synuclein fibrils into the olfactory bulb of mice reduces odor detection sensitivity, detected by plethysmography but not buried pellet tests.

Selective attention controls olfaction in rodents

This study shows that rats can selectively attend to odors amidst competing stimuli, improving odor-guided decisions and sharpening neural representations of odors.

A cortical pathway modulates sensory input into the olfactory striatum

This study investigates the functional role of the cortico-striatal pathway from the piriform cortex to the olfactory tubercle in mice, showing it modulates odor coding through monosynaptic connections.