Discover, rate, and discuss biology papers.

The paper investigates olfactory receptor repertoire variation in New World monkeys, finding that lineage-specific histories, not shared ecological drivers, shape olfactory evolution.

This study examines urban weed response to elevated salt levels through garden experiments, finding some support for salt tolerance adaptation but highlighting environmental heterogeneity and plant variability.

This study uses sparse eGFP labeling to compare astrocyte morphology across brain regions and sexes in mice, finding sex-dependent and region-specific changes after early-life stress.

GIBD detects IBD segments in pangenome graphs and annotates them with structural variants, outperforming existing methods in accuracy and speed.

This study evaluates AAV9-mediated SLC9A6 gene replacement in shaker rats, showing early treatment preserves cerebellar structure and motor function, while later treatment has diminishing effects.

CytoBridge reconstructs continuous virtual cell dynamics from sparse spatial transcriptomic data across development, regeneration, and neurodegeneration.

This study uses genomic analysis to reclassify the Streptococcus anginosus group into four taxa, revealing diversity and lineage-associated traits linked to invasive disease.

This study establishes a scalable ex vivo platform using frozen human skin biopsies to study inflammatory responses in skin structural cells.

The paper shows that Pseudomonas fluorescens protects Chlamydomonas reinhardtii from Pseudomonas protegens by inactivating its toxin protegencin in a tripartite microbial interaction.

JANUS discovers somatic structural variants in cancer genomes using a pangenome graph approach, achieving high accuracy and efficiency compared to traditional methods.

This study examines proteomic changes in Geodermatophilus obscurus G20 under UV stress, showing distinct responses in acute and recovery phases.

The paper examines the balance between apoptosis and arrest-associated transcriptional programs in untreated PDAC, finding a consistent bias toward arrest programs.

The paper shows that during infection, Botrytis cinerea reallocates its transcriptome, altering synonymous codon demand across different host systems.

The paper describes a rare observation of a nocturnal arboreal kinkajou being followed by a puma in a rainforest canopy.

This paper introduces Zindex, a space-efficient indexing framework for large-scale sequence repositories, achieving compact storage and fast query performance with novel interleaved filters and merging mechanisms.

spearfish improves long-read mapping efficiency by leveraging transcriptome redundancy, achieving faster speeds and lower memory usage than existing tools.

This study examines the effects of isocaloric high-fat diet restriction with TAK-242 on metabolic and gut microbial responses in mice, finding limited normalization of adiposity and microbial community.

CausalODE infers gene regulatory networks from single-cell perturbation data by optimizing causal reach, capturing transient dynamics, and modeling latent protein levels, outperforming existing methods on real datasets.

This paper introduces SLAP2, a high-speed microscope for measuring submicron synapses and dendritic voltage in behaving mice, revealing nonlinear input-output amplification in neurons.

RPFace predicts RNA-protein interfaces directly from sequence, outperforming existing methods on RNA interfaces and generalizing to in vivo data without pretraining.