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The paper develops an online decision-making battery to assess reinforcement learning and vigor, finding two distinct factors with moderate reliability and associations with mania but not depression.

This study identifies coding region changes in YAP1 that contribute to body size differences among rodents by showing increased growth-promoting activity in capybara YAP1 compared to mouse and vole YAP1.

This study examines how self-questions drive scientific reasoning in problem solving by analyzing think-aloud interviews of undergraduate life science students.

NEPTUNE identifies neuronal cell death markers from single-cell RNA-seq data, revealing non-apoptotic mechanisms in photoreceptor degeneration in rd1 mice.

The paper introduces DIFFRACT, a framework that uses local fractal dimension changes in protein interaction networks to detect functional reorganization, showing its utility in identifying novel biological roles in RAVER1-deficient cells.

GraphExperiment provides an R/Bioconductor package to store and manipulate high-dimensional quantitative data alongside associated networks in a unified framework.

This study identifies a polar targeting peptide in plants and reveals its evolutionary conservation and diversification within the SOSEKI protein family.

The paper identifies and characterizes a novel resistance haplotype, GpaXIbrc, from Solanum brevicaule that enhances resistance to G. pallida and demonstrates its effectiveness when stacked with other resistance haplotypes.

This paper evaluates the accuracy of structural MRI in classifying autism using leakage-free, site-aware, and externally validated machine learning methods across two ABIDE cohorts, finding modest performance.

This study develops a scalable method to generate functional adipoids from hiPSCs, which mimic human adipose tissue and can be used for metabolic disease research and drug screening.

This study investigates how different molecular crowders affect the magnetic field-dependent fluorescence and recovery kinetics of MagLOV2 in E. coli lysate.

The paper identifies cyclic peptides that selectively bind to a cotranslational folding intermediate of β-galactosidase, revealing a druggable pocket formed during translation.

The paper identifies Saccharomyces cerevisiae and Saccharomyces jurei hybrids with improved oenological traits for wine fermentation.

SpaceBlocks is a workflow for reproducible, expert-supervised spatial transcriptomics analysis across platforms, identifying new cell types and differentially expressed genes in multiple datasets.

This study uses MINFLUX nanoscopy to show nuclear speckles are hierarchically organized into dynamic nanoscale interaction networks that regulate molecular dynamics.

This study identifies the pituitary as a conserved regulator of regeneration across vertebrates, showing its role in limb and fin regeneration through prolactin and growth hormone signaling.

This study shows that lymphangiogenesis is essential for healing and survival after laryngotracheal injury in mice, as blocking it leads to worse outcomes.

The paper benchmarks sparse-to-transcriptome reconstruction models using high-expression profiles from mouse adrenal cells under sex and sex-steroid conditions, finding that gene-wise metrics and strong baselines are critical for evaluation.