Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks
W. M. Schneider, J. M. Luna, H.- H. Hoffmann, F. J. Sanchez-Rivera, A. A. Leal, A. W. Ashbrook, J. Le Pen, E. Michailidis, I. Ricardo-Lax, A. Peace, A. F. Stenzel, S. W. Lowe, M. R. MacDonald, C. M. Rice, J. T. Poirier
The paper identifies host factors required for SARS-CoV-2 and three seasonal coronaviruses using CRISPR screens, revealing shared and virus-specific dependencies.
bioRxiv · Oct 7, 2020Microbiology