Author

A. Allouch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

j.-l. PERFETTINI· 4 shared A. Mostefa-Kara· 2 shared A. Paci· 2 shared D. Tannous· 2 shared A. Deva-Nathan· 1 shared A.-A. Muhammad· 1 shared B. S. Lopez· 1 shared C. Di Primio· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

j.-l. PERFETTINI

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Gadolinium-based nanoparticles AGuIX and their combination with ionizing radiation trigger AMPK-dependent proinflammatory reprogramming of tumor-associated macrophages

Z. Muradova, D. Tannous, A. Mostefa-Kara, T. T. Cao-Pham, C. Lamy, S. Broutin, A. Paci, S. Dufort, T. Doussineau, F. Lux, O. Tillement, G. Le Duc, A. Allouch, j.-l. PERFETTINI

This study shows that AGuIX nanoparticles and their combination with ionizing radiation induce proinflammatory reprogramming of tumor-associated macrophages via AMPK-dependent mitochondrial fragmentation.

bioRxiv · Jan 12, 2024 · PreprintImmunology

The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection

D. Lecuyer, R. Nardacci, D. Tannous, E. Gutierrez-Mateyron, A. Deva-Nathan, F. Subra, C. Di Primio, P. Quaranta, V. Petit, C. Richetta, A. Mostefa-Kara, F. Del Nonno, L. Falasca, R. Marlin, P. Maisonnasse, , J.-L. Perfettini

This study identifies P2X7 and NLRP3 inflammasome as host factors required for SARS-CoV-2 infection and shows their role in promoting viral replication.

bioRxiv · Apr 5, 2023Microbiology

CDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia

A. ALLOUCH, L. VOISIN, Y. ZHANG, R. SYED, Y. LECLUSE, J. CALVO, D. Selimoglu-Buet, S. DE BOTTON, F. LOUACHE, F. PFLUMIO, E. SOLARY, j.-l. PERFETTINI

This study shows that overexpressing CDKN1A in macrophages enhances their ability to phagocytose leukemic cells, leading to pro-inflammatory reprogramming and improved survival in mouse models.

bioRxiv · Jan 18, 2022Immunology

In vivo inactivation of RAD51-mediated homologous recombination leads to premature aging, but not to tumorigenesis

G. Matos-Rodrigues, V. Barroca, A.-A. Muhammad, A. Allouch, S. Koundrioukoff, D. Lewandowski, E. Despras, J. Guirouilh-Barbat, L. Frappart, P. Kannouche, P. Dupaigne, E. Le Cam, J.-L. Perfettini, P.-H. Romeo, M. Debatisse, , B. S. Lopez

This study shows that inactivating RAD51 in mice causes premature aging but not cancer, suggesting RAD51 is critical for progenitor cell homeostasis.

bioRxiv · Jan 17, 2022 · PreprintCancer Biology