Two-dose "extended priming" immunization amplifies humoral immune responses by synchronizing vaccine delivery with the germinal center response
S. Bhagchandani, L. Yang, L. Maiorino, E. Ben-Akiva, K. A. Rodrigues, A. Romanov, H. Suh, A. Aung, S. Wu, A. Wadhera, A. K. Chakraborty, D. J. Irvine
This study shows that a two-dose extended priming vaccine regimen enhances humoral immune responses by synchronizing antigen delivery with germinal center dynamics.
bioRxiv · Nov 20, 2023 · PreprintImmunology