Author

A. B. Theberge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 14 Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 17 Organism:human· 9 Research Focus:cell type annotation· 5 Research Focus:cell signaling & trafficking· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:clustering· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

E. Berthier· 15 shared U. N. Lee· 9 shared X. Su· 6 shared J. Berthier· 5 shared F. Y. Lim· 4 shared M. G. Takezawa· 4 shared S. Thongpang· 4 shared A. J. Haack· 3 shared

Activity by Year

2017-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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15 shared papersBioengineering

E. Berthier

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Author profile →

17 papers

Recent·Most cited

At-home saliva sampling in healthy adults using CandyCollect, a lollipop-inspired device

W.-c. Tu, A. M. McManamen, X. Su, I. Jeacopello, M. G. Takezawa, D. L. Hieber, G. W. Hassan, U. N. Lee, E. V. Anana, M. P. Locknane, M. W. Stephenson, V. A. M. Shinkawa, E. R. Wald, G. P. DeMuri, K. Adams, , A. B. Theberge

The paper demonstrates that the CandyCollect device effectively collects salivary bacteria with 100% concordance with traditional methods and is preferred by users.

Analytical Chemistry · Jun 26, 2023Peer-reviewedBiochemistry

On the dynamic contact angle of capillary-driven microflows in open channels

J. C. Tokihiro, A. M. McManamen, D. N. Phan, S. Thongpang, T. D. Blake, A. B. Theberge, J. Berthier

This study investigates the dynamic contact angle in open channel microflows and finds that it significantly affects fluid penetration, with MKT providing the most accurate predictions.

bioRxiv · Apr 24, 2023Bioengineering

Enhanced capillary pumping using open-channel capillary trees with integrated paper pads

J. C. Tokihiro, W.-c. Tu, J. Berthier, J. J. Lee, A. M. Dostie, J. W. Khor, M. Eakman, A. B. Theberge, E. Berthier

This paper demonstrates enhanced capillary pumping by coupling open-channel capillary trees with paper pads, achieving higher flow rates with viscous liquids.

bioRxiv · Jul 15, 2022Bioengineering

An Open Microfluidic Coculture Model of Fibroblasts and Eosinophils to Investigate Mechanisms of Airway Inflammation

Y. Zeng, X. Su, M. G. Takezawa, P. S. Fichtinger, U. N. Lee, J. W. Pippin, S. J. Shankland, F. Y. Lim, L. C. Denlinger, N. N. Jarjour, S. K. Mathur, N. Sandbo, E. Berthier, S. Esnault, K. Bernau, A. B. Theberge

This paper introduces an open microfluidic coculture model of fibroblasts and eosinophils to study bidirectional signaling in airway inflammation, showing proinflammatory fibroblast activation and potential eosinophil feedback.

bioRxiv · Jul 11, 2022Cell Biology

At-home blood collection and stabilization in high temperature climates using homeRNA

L. G. Brown, A. J. Haack, D. S. Kennedy, K. N. Adams, J. E. Stolarczuk, M. G. Takezawa, E. Berthier, S. Thongpang, F. Y. Lim, D. Chaussabel, M. Garand, A. B. Theberge

This study evaluates the performance of homeRNA, a home-based blood collection and RNA stabilization system, in high-temperature environments, showing acceptable RNA integrity in pilot studies in Qatar and the USA.

bioRxiv · Mar 23, 2022Bioengineering

CandyCollect: At-home saliva sampling for capture of respiratory pathogens

U. N. Lee, X. Su, D. L. Hieber, W.-c. Tu, A. M. McManamen, M. G. Takezawa, G. W. Hassan, T. C. Chan, K. N. Adams, E. R. Wald, G. P. DeMuri, E. Berthier, A. B. Theberge, S. Thongpang

CandyCollect is a saliva sampling device for strep throat diagnosis that improves user experience and captures bacteria effectively for PCR analysis.

bioRxiv · Oct 19, 2021Bioengineering

Freestanding hydrogel lumens for modeling blood vessels and vasodilation

A. M. Dostie, H. G. Lea, U. N. Lee, T. L. van Neel, E. Berthier, A. B. Theberge

This paper introduces an in vitro method to create freestanding hydrogel rings for modeling blood vessels and measuring vasodilator effects, showing significant ring area changes with fasudil.

bioRxiv · Oct 19, 2021Bioengineering

Interfacial tension driven open droplet microfluidics

J. W. Khor, U. N. Lee, J. Berthier, E. Berthier, A. B. Theberge

This paper introduces an open droplet microfluidic system that generates droplets without external pumps, using physical tools for sorting and transfer.

bioRxiv · Jul 29, 2021Bioengineering

Miniaturizing wet scrubbers for aerosolized droplet capture

U. N. Lee, T. L. van Neel, F. Y. Lim, J. W. Khor, J. He, R. S. Vaddi, A. Q. Ong, A. Tang, J. Berthier, J. S. Meschke, I. V. Novosselov, A. B. Theberge, E. Berthier

The paper develops a miniaturized aerosol sampling device inspired by wet scrubbers, demonstrating efficient aerosol capture and viability retention of bioaerosols.

bioRxiv · Mar 23, 2021Bioengineering

homeRNA: A self-sampling kit for the collection of peripheral blood and stabilization of RNA

A. J. Haack, F. Y. Lim, D. S. Kennedy, J. H. Day, K. N. Adams, J. J. Lee, E. Berthier, A. B. Theberge

homeRNA enables self-collection of peripheral blood and stabilization of RNA at home, with high success rates and good RNA quality.

bioRxiv · Feb 8, 2021Bioengineering

Localized cell-surface sampling of a secreted factor using cell-targeting beads

T. L. van Neel, S. B. Berry, E. Berthier, A. B. Theberge

The paper introduces a bead-based system to capture secreted factors from live cells, improving detection compared to traditional supernatant analysis.

bioRxiv · Jun 11, 2020Bioengineering

A modular microscale granuloma model for immune-microenvironment signaling studies in vitro

S. B. Berry, M. S. Gower, X. Su, C. Seshadri, A. B. Theberge

This paper introduces a modular microscale granuloma model to study immune-microenvironment signaling in vitro, showing increased secretion of proinflammatory factors and 3D aggregate formation upon mycobacterial infection.

bioRxiv · Apr 14, 2020Bioengineering

Open microfluidic coculture reveals paracrine signaling from human kidney epithelial cells promotes kidney specificity of endothelial cells

T. Zhang, D. Lih, R. Nagao, J. Xue, E. Berthier, J. Himmelfarb, Y. Zheng, A. B. Theberge

This study uses an open microfluidic coculture system to show that human kidney epithelial cells promote kidney-specific gene expression in endothelial cells through paracrine signaling.

bioRxiv · Feb 14, 2020Bioengineering

Layer-by-Layer Fabrication of 3D Hydrogel Structures Using Open Microfluidics

U. N. Lee, J. H. Day, A. J. Haack, W. Lu, A. B. Theberge, E. Berthier

This paper introduces a layer-by-layer 3D hydrogel fabrication method using open microfluidics and surface tension, enabling the creation of complex structures with minimal dead-volume and shear stress.

bioRxiv · Jun 30, 2019Bioengineering

Investigating Fibroblast-Induced Collagen Gel Contraction Using a Dynamic Microscale Platform

T. Zhang, J. H. Day, X. Su, A. G. Guadarrama, N. K. Sandbo, S. Esnault, L. C. Denlinger, E. Berthier, A. B. Theberge

This study develops a microscale collagen gel contraction assay to investigate fibroblast-induced ECM contraction and intercellular communication in asthma-related fibrosis.

bioRxiv · May 5, 2019Cell Biology

Stable biphasic interfaces for open microfluidic platforms

U. N. Lee, J. Berthier, J. Yu, E. Berthier, A. B. Theberge

This paper introduces an open microfluidic platform for stable aqueous-organic interfaces and develops design rules for varying solvent properties.

bioRxiv · Jan 17, 2019Bioengineering

Fundamentals of rapid injection molding for microfluidic cell-based assays

U. N. Lee, X. Su, D. J. Guckenberger, A. M. Dostie, T. Zhang, E. Berthier, A. B. Theberge

This paper evaluates rapid injection molding for microfluidic device fabrication in cell-based assays, identifying advantages, limitations, and design recommendations for academic use.

bioRxiv · Sep 28, 2017Bioengineering