Author

A. Babosan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

D. Mazel· 4 shared Z. Baharoglu· 4 shared A. Carvalho· 3 shared E. Krin· 2 shared L. Fruchard· 2 shared M. Lang· 2 shared A. Muggeo· 1 shared B. Li· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersMicrobiology

D. Mazel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

RavA-ViaA links Vibrio cholerae Cpx and Zra2 envelope stress to antibiotic response

E. Krin, A. Carvalho, M. Lang, A. Babosan, D. Mazel, Z. Baharoglu

This study shows that deletion of the ravA-viaA operon in Vibrio cholerae increases tolerance to aminoglycosides and affects polymyxin B sensitivity and vancomycin resistance by modulating Cpx and Zra2 two-component systems.

bioRxiv · Apr 24, 2023Microbiology

Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification

L. Fruchard, A. Babosan, A. Carvalho, M. Lang, B. Li, M. Duchateau, Q. Giai Gianetto, M. Matondo, F. Bonhomme, I. Hatin, H. Arbes, C. Fabret, E. Corler, G. Sanchez, V. MArchand, , Z. Baharoglu

This study shows that Q34 modification in tRNA affects translational efficiency in Vibrio cholerae under aminoglycoside stress, leading to reprogramming of gene expression and antibiotic tolerance.

bioRxiv · Sep 26, 2022Microbiology

Non-essential tRNA and rRNA modifications impact the bacterial response to sub-MIC antibiotic stress

A. Babosan, L. Fruchard, E. Krin, A. Carvalho, D. Mazel, Z. Baharoglu

The paper identifies tRNA and rRNA modification genes as critical factors affecting bacterial response to sub-MIC antibiotics from different families.

bioRxiv · Feb 6, 2022Microbiology

A qnr-plasmid allows aminoglycosides to induce SOS in Escherichia coli

A. Babosan, D. Skurnik, A. Muggeo, G. Pier, T. Jove, M.-C. Ploy, S. Griveau, F. Bedioui, S. Vergnolle, S. Moussalih, C. de Champs, D. Mazel, T. Guillard, Z. Baharoglu

The study shows that aminoglycosides can induce the SOS response in E. coli via a qnrD-plasmid, leading to qnrD transcription through NO accumulation driven by plasmid-encoded genes.

bioRxiv · Apr 29, 2021Microbiology