Cell BiologybioRxiv
LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is altered in Townes-Brocks Syndrome
L. Bozal-Basterra, M. Gonzalez-Santamarta, A. Bermejo-Arteagabeitia…·R. Barrio
The paper identifies LUZP1 as a regulator of primary cilia and actin cytoskeleton, showing its role in Townes-Brocks Syndrome through interactions with SALL1 and effects on ciliogenesis and Sonic Hedgehog signaling.
DOI 10.7554/elife.55957