Author

A. Biran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Groth· 3 shared F. Mattiroli· 2 shared G. Ricci· 2 shared A. E. E. Verkennis· 1 shared A. van Oudenaarden· 1 shared A. Wenger· 1 shared B. V. Eckhardt· 1 shared C. Armstrong· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

A. Groth

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Acute multi-level response to defective de novo chromatin assembly in S-phase

J. Dreyer, G. Ricci, J. van den Berg, V. Bhardwaj, J. Funk, C. Armstrong, V. van Batenburg, C. Sine, M. A. Vaninsberghe, R. Marsman, I. K. Mandemaker, S. di Sanzo, J. Costantini, S. Manzo, A. Biran, , F. Mattiroli

This study investigates the acute effects of CAF-1 loss on chromatin assembly during S-phase, revealing multi-level responses including replication slowdown and histone modification changes.

bioRxiv · Mar 22, 2024Cell Biology

Repair of DNA double-strand breaks leaves heritable impairment to genome function

S. C. Bantele, I. Mordini, A. Biran, N. Alcaraz, A. Wenger, N. Krietenstein, A. Groth, J. Lukas

This study shows that DNA double-strand breaks cause lasting chromatin changes that are heritable and impair gene function beyond DNA repair.

bioRxiv · Aug 29, 2023 · PreprintCell Biology

CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands

C. Rouillon, B. V. Eckhardt, L. Kollenstart, F. Gruss, A. E. E. Verkennis, I. Rondeel, P. H. L. Krijger, G. Ricci, A. Biran, T. van Laar, C. M. Delvaux de Fenffe, G. Luppens, P. Albanese, R. A. Scheltema, W. de Laat, , F. Mattiroli

This study shows CAF-1 deposits histones on both DNA strands during replication but uses different mechanisms on leading and lagging strands.

bioRxiv · Oct 14, 2022Biochemistry

Oncogenic addiction to high 26S proteasome levels

P. Tsvetkov, J. Adler, N. Myers, A. Biran, N. Reuven, Y. Shaul

This study shows cancer cells depend on high 26S proteasome levels for survival, and reducing 26S proteasome levels kills cancer cells while sparing normal cells.

bioRxiv · Oct 30, 2017Cancer Biology