Author

F. Mattiroli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Assay:ChIP-seq· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Biran· 2 shared A. Groth· 2 shared B. V. Eckhardt· 2 shared G. Ricci· 2 shared A. E. E. Verkennis· 1 shared A. J. R. Heck· 1 shared A. van Oudenaarden· 1 shared C. Armstrong· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCell Biology

A. Biran

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Author profile →

3 papers

Recent·Most cited

Acute multi-level response to defective de novo chromatin assembly in S-phase

J. Dreyer, G. Ricci, J. van den Berg, V. Bhardwaj, J. Funk, C. Armstrong, V. van Batenburg, C. Sine, M. A. Vaninsberghe, R. Marsman, I. K. Mandemaker, S. di Sanzo, J. Costantini, S. Manzo, A. Biran, , F. Mattiroli

This study investigates the acute effects of CAF-1 loss on chromatin assembly during S-phase, revealing multi-level responses including replication slowdown and histone modification changes.

bioRxiv · Mar 22, 2024Cell Biology

CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands

C. Rouillon, B. V. Eckhardt, L. Kollenstart, F. Gruss, A. E. E. Verkennis, I. Rondeel, P. H. L. Krijger, G. Ricci, A. Biran, T. van Laar, C. M. Delvaux de Fenffe, G. Luppens, P. Albanese, R. A. Scheltema, W. de Laat, , F. Mattiroli

This study shows CAF-1 deposits histones on both DNA strands during replication but uses different mechanisms on leading and lagging strands.

bioRxiv · Oct 14, 2022Biochemistry

Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF

I. Corbeski, X. Guo, B. V. Eckhardt, D. Fasci, W. W. Wiegant, M. Graewert, K. Vreeken, H. Wienk, D. I. Svergun, A. J. R. Heck, H. van Attikum, R. Boelens, T. K. Sixma, F. Mattiroli, H. van Ingen

The paper shows that the acidic domain of APLF assembles histone octamers and deposits them onto DNA to form nucleosomes.

bioRxiv · Dec 24, 2021Biochemistry