Author

A. C. Eddy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Organism:human· 1

Frequent Co-Authors

A. Forero· 3 shared A. Kenney· 2 shared A. Zani· 2 shared C. Cai· 2 shared E. A. Hemann· 2 shared J. Ma· 2 shared J. S. Yount· 2 shared S. Speaks· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersImmunology

A. Forero

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Innate immune control of influenza virus interspecies adaptation

P. J. Denz, S. Speaks, A. D. Kenney, A. C. Eddy, J. L. Papa, J. Roettger, S. C. Scace, E. A. Hemann, A. Forero, R. J. Webby, A. S. Bowman, J. S. Yount

This study shows that IFITM3 deficiency in mice allows avian influenza viruses to infect and adapt more effectively, suggesting a role for IFITM3 in preventing zoonotic virus emergence.

bioRxiv · Aug 23, 2023 · PreprintMicrobiology

Gasdermin D promotes influenza virus-induced mortality through neutrophil amplification of inflammation

S. Speaks, A. Zani, A. Solstad, A. Kenney, M. McFadden, L. Zhang, A. C. Eddy, A. O. Amer, R. Robinson, C. Cai, J. Ma, E. Hemann, A. Forero, J. Yount

This study shows that gasdermin D promotes influenza virus-induced mortality by amplifying neutrophil-driven inflammation.

bioRxiv · Mar 8, 2023Immunology

Interferon-induced transmembrane protein 3 (IFITM3) limits lethality of SARS-CoV-2 in mice

A. Zani, A. Kenney, J. Kawahara, A. C. Eddy, X.-L. Wang, M. KC, M. Lu, E. A. Hemann, J. Li, M. E. Peeples, L. Hall-Stoodley, A. Forero, C. Cai, J. Ma, J. S. Yount

This study shows that IFITM3 protects mice from severe SARS-CoV-2 infection by limiting viral spread and inflammation, as demonstrated through knockout mouse models.

bioRxiv · Dec 22, 2021 · PreprintImmunology