Author

A. C. H. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Cuconati· 1 shared A. G. Cole· 1 shared A. J. Edobor· 1 shared A. M. Lam· 1 shared A. Miller· 1 shared A. S. Kondratowicz· 1 shared B. D. Dorsey· 1 shared B. Tian· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. Cuconati

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2 papers

Recent·Most cited

Host poly(A) polymerases PAPD5 and PAPD7 provide two layers of protection that ensure the integrity and stability of hepatitis B virus RNA

F. Liu, A. C. H. Lee, F. Guo, A. S. Kondratowicz, H. M. Micolochick Steuer, A. Miller, L. D. Bailey, X. Wang, S. Chen, S. G. Kultgen, A. Cuconati, A. G. Cole, D. Gotchev, B. D. Dorsey, R. Rijnbrand, , M. Gao

This study investigates how PAPD5 and PAPD7 stabilize HBV RNA and shows that PAPD5 is dominant in protecting the poly(A) tail, while PAPD7 acts as a backup mechanism.

bioRxiv · Apr 12, 2021Microbiology

Nanotraps for the containment and clearance of SARS-CoV-2

M. Chen, J. Rosenberg, X. Cai, A. C. H. Lee, J. Shi, M. Nguyen, T. Wignakumar, V. Mirle, A. J. Edobor, J. Fung, J. S. Donington, K. Shanmugarajah, E. B. Chang, G. Randall, P. Penaloza-MacMaster, , J. Huang

This paper introduces Nanotraps, functionalized nanoparticles that block SARS-CoV-2 infection by inhibiting spike protein-ACE2 interaction and triggering macrophage-mediated viral clearance.

bioRxiv · Feb 1, 2021Bioengineering