Author

B. Tian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Plant Biology· 3 Microbiology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 6 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:plant (other)· 2

Frequent Co-Authors

H. Chen· 4 shared H. N. Trick· 3 shared E. B. Chang· 2 shared G. Bai· 2 shared J. Huang· 2 shared J. Rosenberg· 2 shared J. Shi· 2 shared M. Chen· 2 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersPlant Biology

H. Chen

Mutual co-authors in cluster

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10 papers

Recent·Most cited

Knowledge Mapping of Alternative Splicing of Cancer From 2012 to 2021: A Bibliometric Analysis

B. Tian, Y. Bian, D.-J. Bian, Y. Gao, X. Zhang, S.-W. Zhou, Y.-H. Zhang, Y.-N. Pang, Z.-S. Li, L.-W. Wang

This paper conducts a bibliometric analysis of cancer alternative splicing research from 2012 to 2021, identifying trends, key institutions, and research areas.

Frontiers in Oncology · Dec 14, 2022Peer-reviewedCancer Biology

Wild-type allele of TaHRC suppresses calcium-mediated plant immune response by hijacking TaCAXIP4 to trigger FHB susceptibility in wheat

H. Chen, Z. Su, B. Tian, G. Hao, H. N. Trick, G. Bai

This study identifies TaHRC as a susceptibility gene for FHB in wheat, showing it suppresses calcium-mediated immune responses by interacting with TaCAXIP4.

bioRxiv · Jun 23, 2022 · PreprintPlant Biology

Development and optimization of a Barley stripe mosaic virus (BSMV)-mediated gene editing system to improve Fusarium head blight (FHB) resistance in wheat

H. Chen, Z. Su, B. Tian, Y. Liu, Y. Pang, V. Kavetskyi, H. N. Trick, G. Bai

This paper develops a BSMV-mediated gene editing system for wheat to improve FHB resistance by editing the Fhb1 gene without requiring transformation.

bioRxiv · Feb 25, 2022Plant Biology

Susceptibilities of human ACE2 genetic variants in coronavirus infection

W. Ren, Y. Zhu, J. Lan, H. Chen, Y. Wang, H. Shi, F. Feng, D.-Y. Chen, B. Close, X. Zhao, J. Wu, B. Tian, Z. Yuan, D. Zhou, M. Saeed, , Q. Ding

The paper investigates how genetic variants in the ACE2 gene affect susceptibility to SARS-CoV-2 infection by analyzing their impact on viral entry.

bioRxiv · Jul 18, 2021Microbiology

Bacterium-Enabled Transient Gene Activation by Artificial Transcription Factor for Resolving Gene Regulation in Maize

M. Zhao, Z. Peng, Y. Qin, L. Zhang, B. Tian, Y. Chen, Y. Liu, G. Lin, H. Zheng, C. He, K. Lv, H. N. Trick, Y. Liu, M.-J. Cho, S. Park, , S. Liu

The paper uses synthetic TAL effectors delivered by bacteria to activate the maize gene gl3, revealing its role in cuticular wax biosynthesis and identifying downstream genes involved in this process.

bioRxiv · Feb 5, 2021Plant Biology

Nanotraps for the containment and clearance of SARS-CoV-2

M. Chen, J. Rosenberg, X. Cai, A. C. H. Lee, J. Shi, M. Nguyen, T. Wignakumar, V. Mirle, A. J. Edobor, J. Fung, J. S. Donington, K. Shanmugarajah, E. B. Chang, G. Randall, P. Penaloza-MacMaster, , J. Huang

This paper introduces Nanotraps, functionalized nanoparticles that block SARS-CoV-2 infection by inhibiting spike protein-ACE2 interaction and triggering macrophage-mediated viral clearance.

bioRxiv · Feb 1, 2021Bioengineering

A Neutralizing Antibody-Conjugated Photothermal Nanoparticle Captures and Inactivates SARS-CoV-2

X. Cai, A. Prominski, Y. Lin, N. Ankenbruck, J. Rosenberg, M. Chen, J. Shi, E. B. Chang, P. Penaloza-MacMaster, B. Tian, J. Huang

This paper develops a photothermal nanoparticle conjugated with neutralizing antibodies to capture and inactivate SARS-CoV-2, showing efficient viral capture, photothermal effect, and inhibition of viral entry.

bioRxiv · Nov 30, 2020 · PreprintBioengineering

Silicon Nanowires for Intracellular Optical Interrogation with Sub-Cellular Resolution

M. Y. Rotenberg, B. Elbaz, V. Nair, E. N. Schaumann, N. Yamamoto, L. Matino, F. Santoro, B. Tian

This paper demonstrates the use of silicon nanowires for sub-cellular optical stimulation in cells, showing their viability, calcium flux induction, and electrical coupling capabilities.

bioRxiv · Oct 31, 2019Bioengineering

A novel antiviral lncRNA EDAL shields a T309 O-GlcNAcylation site to promote EZH2 degradation

L. Zhao, B. Sui, D. Chen, W. Liu, Q. Wu, B. Tian, J. Hou, Y. Li, S. Liu, J. Xie, H. Jiang, Z. Luo, L. Lv, F. Huang, R. Li, , Y. Zhang

This paper identifies a long non-coding RNA, EDAL, that inhibits neurotropic viruses by promoting EZH2 degradation through O-GlcNAcylation site interference.

bioRxiv · Oct 30, 2019 · PreprintMicrobiology

Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite

J. M. Bruning, Y. Wang, F. Oltrabella, B. Tian, S. A. Kholodar, H. Liu, P. Bhattacharya, S. Guo, J. M. Holton, R. J. Fletterick, M. P. Jacobson, P. M. England

The paper identifies 5,6-dihydroxyindole (DHI) as a dopamine metabolite that covalently modifies and activates Nurr1, a nuclear receptor critical for dopaminergic neuron function, offering potential therapeutic strategies for Parkinson's disease.

bioRxiv · Nov 7, 2018Biophysics