Author

S. J. Anthony

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Ecology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:ecology & biodiversity· 2 Assay:metagenomics· 2

Frequent Co-Authors

K. Chandran· 3 shared T. Goldstein· 3 shared A. R. Sjodin· 2 shared B. Lee· 2 shared E. L. Durigon· 2 shared E. Liang· 2 shared G. Lasso· 2 shared H. L. Wells· 2 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

K. Chandran

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Taxonomic classification methods reveal a new subgenus in the paramyxovirus subfamily Orthoparamyxovirinae

H. L. Wells, E. Loh, A. Nava, M. H. Lee, J. Lee, J. R. A. Sukor, I. Navarrete-Macias, E. Liang, C. Firth, J. Epstein, M. Rostal, C. Zambrana-Torrelio, K. A. Murray, P. Daszak, T. Goldstein, , S. J. Anthony

The paper uses taxonomic classification methods to identify a new subgenus in the Orthoparamyxovirinae subfamily based on viral genome sequences from bats.

bioRxiv · Oct 12, 2021Microbiology

Assessing the zoonotic potential of a novel bat morbillivirus

S. Ikegame, J. C. Carmichael, H. Wells, R. L. Furler O'Brien, J. A. Acklin, H.-P. Chiu, K. Y. Oguntuyo, R. M. Cox, A. R. Patel, S. Kowdle, C. S. Stevens, M. Eckley, S. Zhan, J. K. Lim, E. C. Veit, , B. Lee

This study identifies a novel bat morbillivirus, MBaMV, and assesses its zoonotic potential by showing it can infect human cells but is restricted by human immune responses.

bioRxiv · Sep 17, 2021 · PreprintMicrobiology

The evolutionary history of ACE2 usage within the coronavirus subgenus Sarbecovirus

H. L. Wells, M. C. Letko, G. Lasso, B. Ssebide, J. Nziza, D. K. Byarugaba, I. Navarrete-Macias, E. Liang, M. Cranfield, B. A. Han, M. W. Tingley, M. Diuk-Wasser, T. Goldstein, C. Kreuder Johnson, J. Mazet, , S. J. Anthony

This study investigates the evolutionary history of ACE2 usage in sarbecoviruses, showing that ACE2 usage in SARS-CoV-1 and SARS-CoV-2 likely arose through recombination with SARS-CoV-1 relatives, not SARS-CoV-2.

bioRxiv · Jul 7, 2020Evolutionary Biology

Accounting for imperfect detection reveals role of host traits in structuring viral diversity of a wild bat community

A. R. Sjodin, S. J. Anthony, M. R. Willig, M. W. Tingley

The paper uses a community occupancy model to account for imperfect viral detection in wild bats, revealing that host sex and species identity influence viral richness and turnover.

bioRxiv · Jun 29, 2020 · PreprintEcology

A virion-based assay for glycoprotein thermostability reveals key determinants of filovirus entry and its inhibition

R. H. Bortz, A. C. Wong, M. G. Grodus, H. Recht, M. C. Pulanco, G. Lasso, S. J. Anthony, E. Mittler, R. K. Jangra, K. Chandran

This paper introduces an ELISA-based assay to measure the thermostability of filovirus glycoproteins, revealing how proteolytic cleavage, acid pH, and small-molecule inhibitors affect GP stability and viral entry.

bioRxiv · Feb 25, 2020Microbiology

Quantitative delineation of herpesviruses in bats for use in ecological studies

A. R. Sjodin, M. R. Willig, S. J. Anthony

The paper quantitatively analyzes herpesvirus diversity in bat populations to advance ecological understanding of viral communities.

bioRxiv · Nov 26, 2019 · PreprintEcology

Trypsin treatment unlocks barrier for zoonotic coronaviruses infection

V. D. Menachery, K. Dinnon, B. Yount, E. T. McAnarney, L. Gralinski, A. E. Hale, R. Graham, T. D. Scobey, S. J. Anthony, L. Wang, B. S. Graham, S. H. Randell, W. I. Lipkin, R. S. Baric

This study shows that proteolytic cleavage, not receptor binding, is the main barrier for two MERS-like bat coronaviruses to infect human cells, and that trypsin treatment can overcome this barrier.

bioRxiv · Sep 16, 2019Microbiology

Human antibody cocktail deploys multiple functions to confer pan-ebolavirus protection

A. Z. Wec, Z. A. Bornholdt, S. He, A. S. Herbert, E. Goodwin, A. S. Wirchnianski, B. M. Gunn, Z. Zhang, W. Zhu, G. Liu, D. M. Abelson, C. L. Moyer, R. K. Jangra, R. M. James, R. R. Bakken, , K. Chandran

This paper develops a human antibody cocktail, MBP134, that provides broad protection against multiple ebolaviruses, showing enhanced efficacy in guinea pigs compared to individual antibodies.

bioRxiv · Aug 20, 2018Microbiology