Author

A. Cole

Primary ORCID profile (0000-0001-9866-8698 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

A. ColeiD1 paper · Monash University

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Organism:mouse· 1 Organism:non-human primate· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

D. H. Barouch· 2 shared J. Yu· 2 shared M. Gebre· 2 shared N. Roth· 2 shared S. Mueller· 2 shared S. Rauch· 2 shared X. Liu· 2 shared A. Chandrashekar· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

D. H. Barouch

Mutual co-authors in cluster

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3 papers

Recent·Most cited

mRNA Vaccines Induce Rapid Antibody Responses in Mice

M. Gebre, S. Rauch, N. Roth, J. Gergen, J. Yu, X. Liu, A. Cole, S. Mueller, B. W. Petsch, D. H. Barouch

This study shows mRNA vaccines induce rapid antibody responses in mice by day 5, outperforming DNA, protein, and adenovirus vaccines for SARS-CoV-2 and HIV-1 antigens.

bioRxiv · Nov 1, 2021Microbiology

Optimization of Non-Coding Regions Improves Protective Efficacy of an mRNA SARS-CoV-2 Vaccine in Nonhuman Primates

M. Gebre, S. Rauch, N. Roth, J. Yu, A. Chandrashekar, N. Mercado, X. He, J. Liu, K. McMahan, A. Martinot, T. Giffin, D. Hope, S. Patel, D. Sellers, O. Sanborn, , D. H. Barouch

This study compares two mRNA SARS-CoV-2 vaccines in nonhuman primates, showing that CV2CoV, with optimized non-coding regions, provides better immune responses and protection than CVnCoV.

bioRxiv · Aug 13, 2021 · PreprintImmunology

Evolving Bacterial Fitness with an Expanded Genetic Code

D. Tack, A. Cole, R. Shroff, B. R. Morrow, A. Ellington

This study evolves bacteria to use a 21 amino acid genetic code by incorporating an ambiguous amber codon encoding either 3-nitro-L-tyrosine or stop, revealing transitional intermediates in genetic code expansion.

bioRxiv · Jul 28, 2017Evolutionary Biology