Author

A. Martinot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

D. H. Barouch· 3 shared C. Piedra-Mora· 2 shared H. Andersen· 2 shared K. McMahan· 2 shared M. G. Lewis· 2 shared A. Chandrashekar· 1 shared A. Colarusse· 1 shared A. Cole· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

D. H. Barouch

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Reduced Pathogenicity of the SARS-CoV-2 Omicron Variant in Hamsters

K. McMahan, V. Giffin, L. Tostanoski, B. Chung, M. Siamatu, M. Suthar, P. Halfmann, Y. Kawaoka, C. Piedra-Mora, A. Martinot, S. Kar, H. Andersen, M. G. Lewis, D. H. Barouch

This study shows the SARS-CoV-2 Omicron variant causes less weight loss in hamsters than previous variants, suggesting reduced lower respiratory tract disease severity.

bioRxiv · Jan 2, 2022Microbiology

Ad26.COV2.S Prevents SARS-CoV-2 Induced Pathways of Inflammation and Thrombosis in Hamsters

M. Aid, S. Vidal, C. Piedra-Mora, S. Ducat, C. Chan, S. Bondoc, A. Colarusse, C. Starke, M. Nekorchuk, K. Busman-Sahay, J. Estes, A. Martinot, D. H. Barouch

This study shows that Ad26.COV2.S vaccine prevents SARS-CoV-2-induced inflammation and thrombosis in hamsters by reducing proinflammatory and prothrombotic pathways and restoring gene expression profiles to uninfected levels.

bioRxiv · Sep 30, 2021 · PreprintMicrobiology

Optimization of Non-Coding Regions Improves Protective Efficacy of an mRNA SARS-CoV-2 Vaccine in Nonhuman Primates

M. Gebre, S. Rauch, N. Roth, J. Yu, A. Chandrashekar, N. Mercado, X. He, J. Liu, K. McMahan, A. Martinot, T. Giffin, D. Hope, S. Patel, D. Sellers, O. Sanborn, , D. H. Barouch

This study compares two mRNA SARS-CoV-2 vaccines in nonhuman primates, showing that CV2CoV, with optimized non-coding regions, provides better immune responses and protection than CVnCoV.

bioRxiv · Aug 13, 2021 · PreprintImmunology