Author

A. Coscia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Abraham· 2 shared J. Pan· 2 shared L. E. Clark· 2 shared S. A. Clark· 2 shared A. Griffiths· 1 shared C. J. Mann· 1 shared E. A. Ng· 1 shared E. R. May· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

J. Abraham

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural basis for VLDLR recognition by eastern equine encephalitis virus

P. Yang, W. Li, X. Fan, J. Pan, C. J. Mann, H. Varnum, L. E. Clark, S. A. Clark, A. Coscia, K. N. Smith, V. Brusic, J. Abraham

This study determines the structures of EEEV and SFV spike glycoproteins bound to VLDLR, revealing distinct binding modes that explain how different alphaviruses use the same receptor.

bioRxiv · Nov 14, 2023Microbiology

Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2

S. A. Clark, L. E. Clark, J. Pan, A. Coscia, L. G. A. McKay, S. Shankar, R. I. Johnson, A. Griffiths, J. Abraham

The paper identifies germline-biased neutralizing antibodies against SARS-CoV-2 and shows that affinity gains do not always correlate with neutralization potency.

bioRxiv · Nov 13, 2020Microbiology

Molecular Mechanism of Action of Mitochondrial Therapeutic SS-31 (Elamipretide): Membrane Interactions and Effects on Surface Electrostatics

W. Mitchell, E. A. Ng, J. D. Tamucci, K. Boyd, M. Sathappa, A. Coscia, M. Pan, X. Han, N. A. Eddy, E. R. May, H. H. Szeto, N. N. Alder

This paper investigates how SS-31 interacts with mitochondrial membranes, showing it modulates surface electrostatics and lipid packing, supporting its mitoprotective mechanism.

bioRxiv · Aug 14, 2019 · PreprintBiophysics