Author

A. D. Millard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 9

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Assay:metagenomics· 4 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Approach:benchmark study· 2 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1

Frequent Co-Authors

D. J. Stekel· 4 shared J. Hobman· 4 shared R. Cook· 4 shared S. Michniewski· 3 shared T. Redgwell· 3 shared B. Rihtman· 2 shared L. Gannon· 2 shared M. A. Jones· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersMicrobiology

D. J. Stekel

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Author profile →

9 papers

Recent·Most cited

The long and short of it: Benchmarking viromics using Illumina, Nanopore and PacBio sequencing technologies

R. Cook, N. Brown, B. Rihtman, S. Michniewski, T. Redgwell, D. J. Stekel, J. Hobman, Y. Chen, A. Nelson, D. Scanlan, M. A. Jones, D. Smith, A. D. Millard

This paper benchmarks viromics using Illumina, Nanopore, and PacBio sequencing technologies to assess their impact on viral community reconstruction and error rates.

bioRxiv · Feb 12, 2023Microbiology

Lysogenized phages of methanotrophic bacteria show a broad and untapped genetic diversity

M. Stahn, A. Grigonyte, F. D. Orata, D. A. Collins, L. Rieder, M. G. Kalyuzhnaya, A. D. Millard, L. Y. Stein, D. Sauvageau

The paper identifies and characterizes novel phages from methanotrophic bacteria, revealing new phage families and species through genomic and structural analysis.

bioRxiv · May 20, 2022 · PreprintMicrobiology

Antimicrobial resistance in dairy slurry tanks: a critical point for measurement and control

M. Baker, A. D. Williams, S. P. T. Hooton, R. Helliwell, E. King, T. Dodsworth, R. M. Baena-Nogueras, A. Warry, C. A. Ortori, H. Todman, C. J. Gray-Hammerton, A. C. W. Pritchard, E. Iles, R. Cook, R. D. Emes, , D. J. Stekel

This study identifies dairy slurry tanks as critical for antimicrobial resistance (AMR) prevalence and control, showing that 60 days of storage can reduce ARB spread by >99%.

bioRxiv · Feb 22, 2022Microbiology

INfrastructure for a PHAge REference Database: Identification of large-scale biases in the current collection of phage genomes

R. Cook, N. Brown, T. Redgwell, B. Rihtman, M. Barnes, D. J. Stekel, M. Clokie, J. Hobman, M. Jones, A. D. Millard

The paper develops a tool to extract phage genomes and identifies biases in their representation, such as overrepresentation of lytic phages and limited host diversity.

bioRxiv · May 1, 2021Microbiology

Gauge your phage: Benchmarking of bacteriophage identification tools in metagenomic sequencing data

S. F. S. Ho, N. Wheeler, A. D. Millard, W. van Schaik

This study benchmarks ten phage identification tools on metagenomic data, finding VirSorter2 and Kraken2 perform best, with false positives and diversity bias noted.

bioRxiv · Apr 12, 2021 · PreprintMicrobiology

Hybrid assembly of an agricultural slurry virome reveals a diverse and stable community with the potential to alter the metabolism and virulence of veterinary pathogens

R. Cook, S. Hooton, U. Trivedi, L. King, C. Dodd, J. Hobman, D. J. Stekel, M. Jones, A. D. Millard

The paper analyzes the virome of agricultural slurry using hybrid sequencing, revealing a diverse and stable community with potential to influence bacterial metabolism and virulence.

bioRxiv · Oct 8, 2020Microbiology

Isolation and chacterisation of Klebsiella phages for phage therapy

E. Townsend, L. Kelly, L. Gannon, G. Muscatt, R. Dunstan, S. Michniewski, H. Sapkota, S. J. Kiljunen, A. Kolsi, M. Skurnik, T. Lithgow, A. D. MIllard, E. Jameson

This study isolates and characterizes 30 novel Klebsiella phages, finding that lytic phages are most suitable for therapy but single phages are insufficient due to rapid resistance development.

bioRxiv · Jul 5, 2020Microbiology

Genome sequence and characterisation of coliphage vB_Eco_SLUR29

I. Besler, P. Sazinas, C. Harrison, L. Gannon, T. Redgwell, S. Michniewski, S. Hooton, J. Hobman, A. D. Millard

The paper isolates and characterizes a new coliphage from cattle slurry, placing it in a new genus and showing lytic activity dependent on multiplicity of infection.

bioRxiv · Sep 30, 2019 · PreprintMicrobiology

Clostridioides difficile LuxS mediates inter-bacterial interactions within biofilms

R. T. Slater, L. Frost, S. Jossi, A. D. Millard, M. Unnikrishnan

This study shows that C. difficile LuxS/AI-2 mediates biofilm formation and inter-bacterial interactions with B. fragilis through differential metabolic and prophage regulation.

bioRxiv · Dec 13, 2018Microbiology