Author

A. Dema

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 5 Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

J. van Haren· 3 shared T. Wittmann· 3 shared P. Selenko· 2 shared R. A. Charafeddine· 2 shared R. S. Jacob· 2 shared S. Rahgozar· 2 shared A. R. THIAM· 1 shared C. Dumesnil· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

J. van Haren

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

α-Synuclein acts as a cholesteryl-ester sensor on lipid droplets regulating organelle size and abundance.

R. S. Jacob, A. Dema, H. Cherot, C. Dumesnil, S. Cohen, H. S. Shalom, N. Rimon, O. Sibony-Nevo, G. Beck, E. Ainbinder, H. Wolinski, K. Athenstaedt, F.-X. Theillet, A. R. THIAM, P. Selenko

This study shows α-Synuclein binds lipid droplets, senses cholesteryl-ester, regulates organelle size and abundance, and links its dysfunction to neurodegenerative diseases.

bioRxiv · Jun 19, 2024 · PreprintCell Biology

Doublecortin reinforces microtubules to promote growth cone advance in soft environments

A. Dema, R. A. Charafeddine, J. van Haren, S. Rahgozar, G. Viola, K. A. Jacobs, M. L. Kutys, T. Wittmann

This study shows DCX stabilizes microtubules in growth cones, enabling neuron morphogenesis in soft environments by resisting actomyosin contractile forces.

bioRxiv · Feb 28, 2024Cell Biology

Growth cone advance requires EB1 as revealed by genomic replacement with a light-sensitive variant

A. Dema, R. A. Charafeddine, S. Rahgozar, J. van Haren, T. Wittmann

This study replaces endogenous EB1 with a light-sensitive variant in human neurons to show EB1's role in growth cone dynamics and neurite guidance through optogenetic inactivation.

bioRxiv · Sep 22, 2022Cell Biology

Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules

A. Dema, J. van Haren, T. Wittmann

This study uses optogenetic inactivation of EB1 to show that it regulates metaphase spindle length by controlling astral microtubule interactions with cortical dynein/dynactin.

bioRxiv · Sep 29, 2021Cell Biology

α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels.

C. Eichmann, R. S. Jacob, A. Dema, D. Mercadante, P. Selenko

This study shows that phosphatidylinositol polyphosphates mediate α-synuclein's plasma membrane localization in multiple cell types.

bioRxiv · Jul 31, 2020Cell Biology