Author

A. Dunkel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Haller· 2 shared A. Anand· 1 shared A. I. Proano Vasco· 1 shared A. Kuznetsov· 1 shared A. Metwaly· 1 shared A. Riva· 1 shared A. Sorbie· 1 shared C. Meng· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

D. Haller

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Author profile →

2 papers

Recent·Most cited

Microbiota metabolized Bile Acids accelerate Gastroesophageal Adenocarcinoma via FXR inhibition

T. Baumeister, A. I. Proano Vasco, A. Metwaly, K. Kleigrewe, A. Kuznetsov, L. Schoemig, M. Borgmann, M. Khiat, A. Anand, K. Boettcher, D. Haller, A. Dunkel, V. Somoza, S. Reiter, C. Meng, , M. Quante

This study shows that high-fat diets promote GEAC by altering the microbiota-Bile Acid axis and inhibiting FXR, with FXR agonists like OCA slowing disease progression.

bioRxiv · Jun 11, 2024 · PreprintCancer Biology

ATF6 activation alters colonic lipid metabolism causing tumor-associated microbial adaptation

O. I. Coleman, A. Sorbie, A. Riva, M. von Stern, S. Kuhls, D. Selegato, N. Koehler, J. Wirbel, T. Kacprowski, A. Dunkel, J. K. Pauling, J. Plagge, D. Miedel-Cuadra, S. Wagner, I. Chadly, , D. Haller

This study shows ATF6 activation in colonic epithelial cells alters lipid metabolism, promoting tumor-associated microbial adaptation in mice and human colorectal cancer patients.

bioRxiv · Nov 3, 2023 · PreprintCancer Biology