Author

A. E. Jaffe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. Xu· 1 shared D. C. Sarver· 1 shared F. J. Gao· 1 shared G. W. Wong· 1 shared H. Kuri-Magana· 1 shared H. Valdovinos-Torres· 1 shared J. M. Tellez-Sosa· 1 shared J. Martinez-Barnetche· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

C. Xu

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2 papers

Recent·Most cited

Hypermetabolism in mice carrying a near complete human chromosome 21

D. C. Sarver, C. Xu, S. Rodriguez, S. Aja, A. E. Jaffe, F. J. Gao, M. Delannoy, M. Periasamy, Y. Kazuki, M. Oshimura, R. H. Reeves, G. W. Wong

This study shows that mice with a human chromosome 21 exhibit hypermetabolism, hyperactivity, and increased insulin sensitivity due to sarcolipin overexpression in skeletal muscle.

bioRxiv · Jan 30, 2023Physiology

Non-coding Class Switch Recombination-related transcription in human normal and pathological immune responses

H. Kuri-Magana, L. Collado-Torres, A. E. Jaffe, H. Valdovinos-Torres, M. Ovilla-Munoz, J. M. Tellez-Sosa, L. C. Bonifaz-Alfonzo, J. Martinez-Barnetche

The paper analyzes non-coding class switch recombination (CSRnc) transcription in human tissues and diseases using RNA-seq data, finding it widespread in B cells and associated with immune responses.

bioRxiv · Aug 3, 2018Immunology