Author

Y. Kazuki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. E. Jaffe· 1 shared C. Xu· 1 shared D. C. Sarver· 1 shared F. J. Gao· 1 shared G. W. Wong· 1 shared I. Yokoseki· 1 shared K. Kobayashi· 1 shared K. Kurosawa· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

A. E. Jaffe

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2 papers

Recent·Most cited

ncBAF, a chromatin remodeler, enhances PXR-mediated transcriptional activation in the human and mouse liver

K. Kurosawa, M. Nakano, I. Yokoseki, M. Nagaoka, S. Takemoto, Y. Sakai, K. Kobayashi, Y. Kazuki, T. Fukami, M. Nakajima

This study shows that inhibiting BRD9, a component of ncBAF, reduces PXR-mediated transcriptional activation and associated adverse effects in liver cells and mice.

bioRxiv · Feb 3, 2023 · PreprintPharmacology & Toxicology

Hypermetabolism in mice carrying a near complete human chromosome 21

D. C. Sarver, C. Xu, S. Rodriguez, S. Aja, A. E. Jaffe, F. J. Gao, M. Delannoy, M. Periasamy, Y. Kazuki, M. Oshimura, R. H. Reeves, G. W. Wong

This study shows that mice with a human chromosome 21 exhibit hypermetabolism, hyperactivity, and increased insulin sensitivity due to sarcolipin overexpression in skeletal muscle.

bioRxiv · Jan 30, 2023Physiology