Author

A. E. P. Loftus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Byron· 3 shared M. C. Frame· 3 shared A. von Kriegsheim· 2 shared B. G. C. Griffith· 2 shared J. C. Dawson· 2 shared V. G. Brunton· 2 shared A. Herrero· 1 shared A. Nguyen Phuong· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCell Biology

A. Byron

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A novel ILK/STAT3 pathway controls plasticity in a neural stem cell model of glioblastoma.

A. E. P. Loftus, M. S. Romano, A. Nguyen Phuong, M. T. Muir, J. C. Dawson, L. Avalle, A. T. Douglas, R. L. Mort, A. Byron, N. O. Carragher, S. M. Pollard, V. G. Brunton, M. C. Frame

This study identifies a novel ILK-STAT3 pathway that regulates phenotypic plasticity and mesenchymal state in mouse glioblastoma stem cells.

bioRxiv · Jul 19, 2023 · PreprintCancer Biology

Characterisation of a nucleo-adhesome

A. Byron, B. G. C. Griffith, A. Herrero, A. E. P. Loftus, E. S. Koeleman, J. C. Dawson, L. Kogerman, N. McGivern, J. Culley, G. R. Grimes, B. Serrels, A. von Kriegsheim, V. G. Brunton, M. C. Frame

The paper identifies a nucleo-adhesome, showing that adhesion proteins localize to the nucleus and regulate transcription through interactions like FAK and Hic-5.

bioRxiv · Aug 31, 2021Cell Biology

Mena regulates the LINC complex to control actin-nuclear lamina associations, trans-nuclear membrane signalling and cancer gene expression

F. Li Mow Chee, B. Beernaert, A. E. P. Loftus, Y. Kumar, B. G. C. Griffith, J. C. Wills, A. P. Wheeler, J. D. Armstrong, M. Parsons, I. M. Leigh, C. M. Proby, A. von Kriegsheim, W. A. Bickmore, M. C. Frame, A. Byron

This study identifies Mena's role in regulating the LINC complex and nuclear architecture, linking it to cancer gene expression through nuclear membrane signaling.

bioRxiv · Aug 31, 2021 · PreprintCell Biology