Endosomal free fatty acid receptor 2 signaling is essential for propionate-induced anorectic gut hormone release
N. Caengprasath, N. Gonzalez-Abuin, M. Shchepinova, Y. Ma, A. Inoue, E. W. Tate, G. Frost, A. Hanyaloglu
This study shows propionate activates endosomal Gi/p38 signaling via FFA2 to induce GLP-1 release in enteroendocrine cells.
bioRxiv · Mar 24, 2020Cell Biology