Author

G. Frost

University of Exeter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Genetic & Genomic Medicine· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

E. W. Tate· 2 shared A. C. Hanyaloglu· 1 shared A. Dagbasi· 1 shared A. Forman· 1 shared A. Fritsche· 1 shared A. Hanyaloglu· 1 shared A. Holliday· 1 shared A. Inoue· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

E. W. Tate

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Modelling the gut microbiota of children with malnutrition: in vitro models reveal differences in fermentability of widely consumed carbohydrates

J. Ahn-Jarvis, K. R. Corbin, S. C. Harris, P. Rey, P. Olupot-Olupot, N. Calder, K. Walsh, K. Maitland, G. Frost, F. Warren

This study uses an in vitro model to show that inulin is poorly fermented by the gut microbiota of children with severe acute malnutrition, while legume-based feeds and milk oligosaccharides are more effectively fermented.

bioRxiv · May 8, 2024 · PreprintMicrobiology

Augmented gut hormone response to feeding in older adults exhibiting low appetite.

A. Dagbasi, J. Warner, V. Catterall, D. R. Crabtree, B. Carroll, G. Frost, A. Holliday

This study compares gut hormone responses to feeding in older adults with low appetite versus healthy appetite and young adults, finding augmented anorexigenic responses in older adults with low appetite.

bioRxiv · Dec 29, 2023Physiology

Pharmacogenomics of GLP-1 Receptor Agonists: A genome-wide analysis of observational data and large randomized controlled trials

Adem Y. Dawed, Andrea Mari, Andrew Anand Brown, Timothy James McDonald, Lin Li, Shuaicheng Wang, Mun‐Gwan Hong, Sapna Sharma, Neil R. Robertson, Anubha Mahajan, Xuan Wang, Mark Walker, Stephen Charles Langford Gough, Leen M. ‘t Hart, Kaixin Zhou, , A. Jonsson

This study identifies genetic variants associated with glycaemic response to GLP-1 receptor agonists using observational and trial data, finding variants in GLP-1R and ARRB1 linked to HbA1c reduction.

The Lancet Diabetes & Endocrinology · Dec 15, 2022Peer-reviewedGenetic & Genomic Medicine

Short chain fatty acids enhance expression and activity of the umami taste receptor in enteroendocrine cells via a Gαi/o pathway

M. Shackley, A. J. H. Brown, E. W. Tate, G. Frost, A. C. Hanyaloglu

This study shows SCFAs enhance umami receptor expression in EECs via Gi/o signaling, improving nutrient sensing without affecting SCFA GPCRs.

bioRxiv · Jun 1, 2020Cell Biology

Endosomal free fatty acid receptor 2 signaling is essential for propionate-induced anorectic gut hormone release

N. Caengprasath, N. Gonzalez-Abuin, M. Shchepinova, Y. Ma, A. Inoue, E. W. Tate, G. Frost, A. Hanyaloglu

This study shows propionate activates endosomal Gi/p38 signaling via FFA2 to induce GLP-1 release in enteroendocrine cells.

bioRxiv · Mar 24, 2020Cell Biology