Adenosine and acute low oxygen conditions suppress urinary bladder contractility through the activation of adenosine 2B receptors and large-conductance calcium-activated potassium channels
Gerald M. Herrera, Thomas Jon Heppner, Grant W. Hennig, Jason L. Rengo, A. Hepp, María Sancho, Saúl Huerta de la Cruz, Mark T. Nelson, Nicholas R. Klug
This study shows adenosine and low oxygen reduce bladder contractility via A2B receptors and BKCa channels in mice.
The Journal of Physiology · Oct 29, 2025Peer-reviewedPhysiology