Author

Thomas Jon Heppner

University of VermontORCID 0000-0001-8052-7192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:electronic health records· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1

Frequent Co-Authors

Mark T. NelsoniD· 3 shared Nicholas R. KlugiD· 3 shared Gerald M. HerreraiD· 2 shared Grant W. HennigiD· 2 shared Jason L. RengoiD· 2 shared María SanchoiD· 2 shared Saúl Huerta de la CruziD· 2 shared A. Hepp· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersPhysiology

Mark T. NelsonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PhysiologybioRxivPreprintAug 14, 2026

G-protein coupled receptor activity mediates detrusor smooth muscle phasic contractility through regulation of membrane potential

Jason L. Rengo, Thomas Jon Heppner, Grant W. Hennig…·Gerald M. Herrera

This study investigates how GqPCR activity regulates detrusor smooth muscle phasic contractions and transient pressure events through effects on Ca2+ activity and membrane potential.

DOI 10.64898/2026.08.10.743960

mouseelectronic health records

𝕏 PostBluesky

PhysiologyThe Journal of PhysiologyPeer-reviewedOct 29, 2025

Adenosine and acute low oxygen conditions suppress urinary bladder contractility through the activation of adenosine 2B receptors and large-conductance calcium-activated potassium channels

Gerald M. Herrera, Thomas Jon Heppner, Grant W. Hennig…·Nicholas R. Klug

This study shows adenosine and low oxygen reduce bladder contractility via A2B receptors and BKCa channels in mice.

1 citation

mouseelectrophysiology

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NeuroscienceScience SignalingPeer-reviewedMar 29, 2022

Electro-Metabolic Sensing Through Capillary ATP-Sensitive K+ Channels and Adenosine to Control Cerebral Blood Flow

María Sancho, Nicholas R. Klug, Amreen Mughal…·Mark T. Nelson

The paper demonstrates that brain capillary endothelial cells and pericytes express functional KATP channels that regulate membrane potential and cerebral blood flow through adenosine signaling.

98 citationstop 3%

mouseelectronic health records

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