ImmunologybioRxivPreprint
WNT6-ACC2-induced accumulation of triacylglycerol rich lipid droplets is exploited by Mycobacterium tuberculosis
J. Brandenburg, S. Marwitz, S. C. Tazoll…·N. Reiling
This study shows that the WNT6-ACC2 pathway promotes lipid droplet accumulation in macrophages, which Mycobacterium tuberculosis exploits for growth, and that inhibiting this pathway enhances anti-tuberculosis treatment.
DOI 10.1101/2020.06.26.174110