Detection of Mycobacterium tuberculosis in human tissue via RNA in situ hybridization
k. Nargan, T. Naidoo, M. Msimang, S. Nadeem, G. Wells, R. L. Hunter, A. Hutton, K. Lumamba, J. N. Glasgow, P. V. Benson, A. J. Steyn
This paper uses RNA in situ hybridization to detect Mycobacterium tuberculosis mRNA in human tissue, identifying Mtb in ZN-negative samples and revealing two distinct Mtb populations.
bioRxiv · Oct 4, 2023 · PreprintMicrobiology