SWELL1-LRRC8 complex regulates skeletal muscle cell size, intracellular signalling, adiposity and glucose metabolism
A. Kumar, L. Xie, C. M. Ta, A. J. Hinton, S. K. Gunasekar, R. A. Minerath, K. Shen, J. M. Maurer, C. E. Grueter, E. D. Abel, G. Meyer, R. Sah
This study identifies the SWELL1-LRRC8 complex as a mechanosensor regulating skeletal muscle size, signaling, adiposity, and glucose metabolism through PI3K-AKT-mTOR pathways.
bioRxiv · Jun 4, 2020Cell Biology