Targeting a proteolytic neo-epitope of CUB-domain containing protein 1 in RAS-driven cancer
S. A. Lim, J. Zhou, A. J. Martinko, Y.-H. Wang, E. V. Filippova, V. Steri, D. Wang, S. G. Remesh, J. Liu, B. Hann, A. A. Kossiakoff, M. J. Evans, K. K. Leung, J. A. Wells
The paper develops antibodies targeting proteolytic neo-epitopes of CDCP1 in RAS-driven cancers, showing improved tumor specificity and safety.
bioRxiv · Jun 14, 2021 · PreprintBiochemistry