Author

A. J. Simpkin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

D. J. Rigden· 2 shared C. V. Pulford· 1 shared D. A. Rasko· 1 shared E. M. Barry· 1 shared E. Westhof· 1 shared F. Bu· 1 shared K. S. Baker· 1 shared M. Topf· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

D. J. Rigden

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2 papers

Recent·Most cited

Assessment of three-dimensional RNA structure prediction in CASP15

R. Das, R. C. Kretsch, A. J. Simpkin, T. Mulvaney, P. Pham, R. Rangan, F. Bu, R. M. Keegan, M. Topf, D. J. Rigden, Z. Miao, E. Westhof

This paper evaluates RNA 3D structure prediction methods in CASP15, finding that non-deep learning groups outperformed deep learning models, with challenges in fine details and model ranking.

bioRxiv · Apr 25, 2023Biophysics

Informing shigellosis prevention and control through pathogen genomics

R. J. Bengtsson, A. J. Simpkin, C. V. Pulford, R. Low, D. A. Rasko, D. J. Rigden, N. Hall, E. M. Barry, S. M. Tennant, K. S. Baker

This study uses genomic analysis of Shigella strains from seven LMIC to show S. sonnei's high disease contribution and convergent antimicrobial resistance evolution, highlighting the need for updated vaccine and treatment strategies.

bioRxiv · Jun 9, 2021 · PreprintMicrobiology