Cardiac fibroblasts regulate cardiomyocyte hypertrophy through dynamic regulation of type I collagen
Q. Meng, S. L. K. Bowers, Y. Kuwabara, J. Huo, R. Minerath, A. J. York, M. A. Sargent, V. Prasad, A. J. Saviola, D. C. Galindo, K. C. Hansen, R. J. Vagnozzi, K. E. Yutzey, J. D. Molkentin
This study shows that type I collagen produced by cardiac fibroblasts regulates cardiomyocyte hypertrophy and fibrosis, with developmental and acute deletion effects on cardiac function.
bioRxiv · May 25, 2022 · PreprintCell Biology