Author

V. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. J. York· 1 shared A. K. Johansen· 1 shared A. Klestzick· 1 shared A. Murison· 1 shared A. Oza· 1 shared C. Duan· 1 shared C. Hachicho· 1 shared C. L. Vizcarra· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A. J. York

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Local administration of a novel siRNA modality into the CNS extends survival and improves motor function in the SOD1G93A mouse model for ALS

C. Duan, M. Kang, X. Pan, Z. Gan, V. Huang, G. Li, R. F. Place, L.-C. Li

This study demonstrates that a novel siRNA modality, conjugated with an accessory oligonucleotide, improves survival and motor function in a mouse model of ALS when delivered locally to the CNS.

bioRxiv · Feb 27, 2023 · PreprintCell Biology

Alterations to the broad-spectrum formin inhibitor SMIFH2 improve potency

M. Orman, M. Landis, A. Oza, D. Nambiar, J. Gjeci, K. Song, V. Huang, A. Klestzick, C. Hachicho, S. Q. Liu, J. M. Kamm, F. Bartolini, J. J. Vadakkan, C. M. Rojas, C. L. Vizcarra

The paper tests SMIFH2 and its derivatives against human formins, finding that modifications enhance potency but do not allow distinction between conserved FH2 domains.

bioRxiv · Mar 10, 2022 · PreprintBiochemistry

An acute immune response underlies the benefit of cardiac adult stem cell therapy

R. Vagnozzi, M. Maillet, M. Sargent, H. Khalil, A. K. Johansen, J. Schwanekamp, A. J. York, V. Huang, M. Nahrendorf, S. Sadayappan, J. D. Molkentin

This study shows that cardiac adult stem cell therapy improves heart function through an acute immune response involving macrophages, not by regenerating cardiomyocytes.

bioRxiv · Dec 26, 2018Cell Biology

Candidate cancer driver mutations in super-enhancers and long-range chromatin interaction networks

L. Wadi, L. Uuskula-Reimand, K. Isaev, S. Shuai, V. Huang, M. Liang, D. Thompson, Y. Li, L. Ruan, M. Paczkowska, M. Krassowski, I. Dzneladze, K. Kron, A. Murison, P. Mazrooei, , J. Reimand

The paper identifies 41 frequently mutated regulatory elements in cancer genomes, enriched in non-coding mutations and linked to gene expression control through chromatin interactions.

bioRxiv · Dec 19, 2017Cancer Biology