Author

M. Nahrendorf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 5 Research Focus:development & morphogenesis· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:electrophysiology· 1

Frequent Co-Authors

M. J. Schloss· 3 shared D. Rohde· 2 shared G. Wojtkiewicz· 2 shared R. Weissleder· 2 shared Y. Iwamoto· 2 shared A. Bapat· 1 shared A. E. Boitano· 1 shared A. J. York· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersPhysiology

M. J. Schloss

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer

K. Gustafsson, C. Rhee, V. Frodermann, E. W. Scadden, Y. Iwamoto, R. Palchaudhuri, S. L. Hyzy, A. E. Boitano, M. Nahrendorf, D. Scadden

This study shows that anti-CD45-ADC clears tissue-resident myeloid cells, enabling efficient replacement with donor cells and reducing atherosclerotic plaque burden.

bioRxiv · Sep 5, 2023 · PreprintImmunology

Cerebrospinal fluid outflow through skull channels instructs cranial hematopoiesis

F. E. Pulous, J. C. Cruz-Hernandez, C. Yang, Z. Kaya, G. Wojtkiewicz, D. Capen, D. Brown, J. W. Wu, C. Vinego, M. Yamazoe, J. Grune, M. J. Schloss, D. Rohde, D. Richter, C. S. McAlpine, , M. Nahrendorf

The paper shows cerebrospinal fluid exits through skull channels into bone marrow, and bacteria use this route during meningitis to initiate cranial hematopoiesis.

bioRxiv · Aug 27, 2021 · PreprintImmunology

Genetic Inhibition of Serum Glucocorticoid Kinase 1 Prevents Obesity-related Atrial Fibrillation

A. Bapat, G. Li, L. Xiao, M. Hulsmans, M. J. Schloss, Y. Iwamoto, J. Tedeschi, X. Yang, M. Nahrendorf, A. Rosenzweig, P. Ellinor, S. Das, D. Milan

This study shows that genetic inhibition of SGK1 reduces obesity-related atrial fibrillation in mice by decreasing fibrosis, inflammation, and altering electrophysiology.

bioRxiv · May 20, 2021Physiology

A mouse model of recurrent myocardial infarction reports diminished emergency hematopoiesis and cardiac inflammation

S. Cremer, M. J. Schloss, C. Vinegoni, S. Zhang, D. Rohde, P. F. Feruglio, S. Schmidt, G. Wojtkiewicz, R. Weissleder, F. Swirski, M. Nahrendorf

This study develops a mouse model of recurrent myocardial infarction and finds that prior MI reduces emergency hematopoiesis and immune response to subsequent cardiac injury.

bioRxiv · Jun 4, 2019Physiology

An acute immune response underlies the benefit of cardiac adult stem cell therapy

R. Vagnozzi, M. Maillet, M. Sargent, H. Khalil, A. K. Johansen, J. Schwanekamp, A. J. York, V. Huang, M. Nahrendorf, S. Sadayappan, J. D. Molkentin

This study shows that cardiac adult stem cell therapy improves heart function through an acute immune response involving macrophages, not by regenerating cardiomyocytes.

bioRxiv · Dec 26, 2018Cell Biology