Author

A. J. Zwetsloot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Straube· 3 shared D. Roth· 2 shared N. Siddiqui· 2 shared A. Bachmann· 1 shared A. P. Carter· 1 shared A. Toleikis· 1 shared C. E. Stone· 1 shared F. A. Ali· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

A. Straube

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3 papers

Recent·Most cited

KIF1C activates and extends dynein movement through the FHF cargo adaptor

F. A. Ali, A. J. Zwetsloot, C. E. Stone, T. E. Morgan, R. F. Wademan, A. P. Carter, A. Straube

The paper shows KIF1C activates and enhances dynein movement via the FHF cargo adaptor, revealing a mechanism for motor co-dependency.

bioRxiv · Oct 26, 2023Cell Biology

Force generation of KIF1C is impaired by pathogenic mutations

N. Siddiqui, D. Roth, A. Toleikis, A. J. Zwetsloot, R. A. Cross, A. Straube

This study investigates the force generation of KIF1C and shows that pathogenic mutations impair its ability to generate force, leading to neuronal dysfunction.

bioRxiv · Jun 30, 2021Cell Biology

Activation of intracellular transport by relieving KIF1C autoinhibition

N. Siddiqui, A. Bachmann, A. J. Zwetsloot, H. Hussain, D. Roth, I. Kaverina, A. Straube

This study identifies how PTPN21 relieves KIF1C autoinhibition, enabling cargo-specific transport and bidirectional movement.

bioRxiv · Dec 6, 2018Cell Biology