Author

A. Straube

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1 Assay:structural biology· 1

Frequent Co-Authors

A. J. Zwetsloot· 3 shared D. Roth· 3 shared N. Siddiqui· 3 shared A. Toleikis· 2 shared R. A. Cross· 2 shared A. Bachmann· 1 shared A. M. Fry· 1 shared A. P. Carter· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

A. J. Zwetsloot

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

KIF1C activates and extends dynein movement through the FHF cargo adaptor

F. A. Ali, A. J. Zwetsloot, C. E. Stone, T. E. Morgan, R. F. Wademan, A. P. Carter, A. Straube

The paper shows KIF1C activates and enhances dynein movement via the FHF cargo adaptor, revealing a mechanism for motor co-dependency.

bioRxiv · Oct 26, 2023Cell Biology

Force generation of KIF1C is impaired by pathogenic mutations

N. Siddiqui, D. Roth, A. Toleikis, A. J. Zwetsloot, R. A. Cross, A. Straube

This study investigates the force generation of KIF1C and shows that pathogenic mutations impair its ability to generate force, leading to neuronal dysfunction.

bioRxiv · Jun 30, 2021Cell Biology

Activation of cytoplasmic dynein through microtubule crossbridging

M. Chakraborty, A. Toleikis, N. Siddiqui, R. A. Cross, A. Straube

This study shows that cytoplasmic dynein can crossbridge microtubules, enabling it to slide and polarity-sort microtubule bundles without requiring dynactin or cargo adapters.

bioRxiv · Apr 13, 2020 · PreprintBiophysics

Activation of intracellular transport by relieving KIF1C autoinhibition

N. Siddiqui, A. Bachmann, A. J. Zwetsloot, H. Hussain, D. Roth, I. Kaverina, A. Straube

This study identifies how PTPN21 relieves KIF1C autoinhibition, enabling cargo-specific transport and bidirectional movement.

bioRxiv · Dec 6, 2018Cell Biology

Mitotic phosphorylation by Nek6 and Nek7 reduces microtubule affinity of EML4 to alter spindle dynamics and promote chromosome congression

A. M. Fry, R. Adib, J. M. Montgomery, J. Atherton, L. O'Regan, M. Richards, K. R. Straatman, D. Roth, A. Straube, R. Bayliss, C. A. Moores

bioRxiv · Nov 9, 2018Cell Biology