Author

A. K. Fielding

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Akarca· 1 shared A. Dey· 1 shared A. Gutierrez· 1 shared A. Turna· 1 shared D. Auty· 1 shared D. O'Connor· 1 shared E. Cutler· 1 shared G. Bloye· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Akarca

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Author profile →

2 papers

Recent·Most cited

Focal Deletions of a Promoter Tether Activate the IRX3 Oncogene in T Cell Acute Lymphoblastic Leukemia

S. Rahman, G. Bloye, N. Farah, J. Demeulemeester, J. R. Costa, D. O'Connor, R. Pocock, A. Turna, L. Wang, S. Lee, A. K. Fielding, J. Roels, R. Jaksik, M. Dawidowska, P. V. Vlierberghe, , M. R. Mansour

The paper identifies a novel mechanism where focal deletions of an intronic element in FTO lead to IRX3 activation in T-ALL through enhancer hijacking.

bioRxiv · Feb 6, 2024Cancer Biology

Mitochondrial dsRNA from B-ALL cells stimulates mesenchymal stromal cells to become cancer associated fibroblasts

R. J. Burt, A. Dey, A. Akarca, H. Allen, R. Amerikanou, S. Atkinson, D. Auty, J. Chatzigerou, E. Cutler, J. A. Guerra-Assuncao, K. Kirschner, R. Kumari, J. Manji, T. Marafioti, A. K. Fielding

This study shows that mitochondrial dsRNA from B-ALL cells triggers MSC to become CAFs, linking genetic subtypes to survival outcomes.

bioRxiv · Sep 26, 2023Cancer Biology