Author

A. K. O'Connell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

F. Douam· 3 shared M. Bosmann· 3 shared A. Emili· 2 shared B. Blum· 2 shared D. Kenney· 2 shared H. P. Gertje· 2 shared J. H. Connor· 2 shared M. Ericsson· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

F. Douam

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1Omicron

D.-Y. Chen, D. Kenney, C.-V. Chin, A. H. Tavares, N. Khan, H. L. Conway, G. Liu, M. C. Choudhary, H. P. Gertje, A. K. O'Connell, D. N. Kotton, A. Herrmann, A. Ensser, J. H. Connor, M. Bosmann, , M. Saeed

This study compares the pathogenicity and immune evasion of an Omicron S-bearing virus with natural Omicron, showing vaccine escape via S mutations but severe disease due to factors outside S.

bioRxiv · Oct 13, 2022 · PreprintMicrobiology

Platelet proteome analysis reveals an early hyperactive phenotype in SARS-CoV-2-infected humanized ACE2 mice

S. Subramaniam, R. M. Hekman, A. Jayaraman, A. K. O'Connell, P. Montanaro, B. Blum, D. Kenney, M. Ericsson, K. Ravid, N. A Crossland, A. Emili, F. Douam, M. Bosmann

This paper uses proteomics to analyze platelet changes in SARS-CoV-2-infected humanized mice, finding early activation of coagulation and complement pathways.

bioRxiv · Aug 19, 2021 · PreprintImmunology

Macrophages govern antiviral responses in human lung tissues protected from SARS-CoV-2 infection

D. J. Kenney, A. K. O'Connell, J. Turcinovic, P. Montanaro, R. M. Hekman, T. Tamura, A. R. Berneshawi, T. R. Cafiero, S. Al Abdullatif, B. Blum, S. I. Goldstein, B. Heller, H. P. Gertje, E. Bullitt, A. J. Trachtenberg, , F. Douam

This study shows that macrophages mediate antiviral responses in human lung tissues, protecting against SARS-CoV-2 infection through the USP18-ISG15 axis.

bioRxiv · Jul 17, 2021 · PreprintMicrobiology