Author

D. J. Kenney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. B. Balazs· 2 shared A. K. O'Connell· 2 shared F. Douam· 2 shared H. P. Gertje· 2 shared J. H. Connor· 2 shared J. Turcinovic· 2 shared M. Ericsson· 2 shared N. A. Crossland· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. B. Balazs

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Immune Signatures of SARS-CoV-2 Infection Resolution in Human Lung Tissues

D. J. Kenney, A. K. O'Connell, A. E. Tseng, J. Turcinovic, M. L. Sheahan, A. D. Nitido, P. Montanaro, H. P. Gertje, M. Ericsson, J. H. Connor, V. Vrbanac, N. A. Crossland, C. Harly, A. B. Balazs, F. Douam

This study identifies immune signatures associated with SARS-CoV-2 infection resolution in human lung tissues using a humanized mouse model.

bioRxiv · Mar 8, 2024Immunology

Macrophages govern antiviral responses in human lung tissues protected from SARS-CoV-2 infection

D. J. Kenney, A. K. O'Connell, J. Turcinovic, P. Montanaro, R. M. Hekman, T. Tamura, A. R. Berneshawi, T. R. Cafiero, S. Al Abdullatif, B. Blum, S. I. Goldstein, B. Heller, H. P. Gertje, E. Bullitt, A. J. Trachtenberg, , F. Douam

This study shows that macrophages mediate antiviral responses in human lung tissues, protecting against SARS-CoV-2 infection through the USP18-ISG15 axis.

bioRxiv · Jul 17, 2021 · PreprintMicrobiology

Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry

W. Ren, G. Hu, X. Zhao, Y. Wang, H. Shi, J. Lan, Y. Zhu, J. Wu, D. J. Kenney, D. Florian, Y. Tong, J. Zhong, Y. Xie, X. Wang, Z. Yuan, , Q. Ding

The paper identifies species-specific genetic differences in ACE2 that determine SARS-CoV-2 entry capability and shows that humanizing these residues in koala and mouse ACE2 enables viral entry.

bioRxiv · Sep 20, 2020Microbiology